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Why Choose Just One?

The UK is planning a clinical trial for next year to test whether giving people doses of different SARS-CoV-2 vaccines will provide better protection than two doses of the same vaccine, according to the Guardian.

The trial, it says, is to begin in January if the vaccine from AstraZeneca and Oxford University gains authorization. Participants would receive one dose of that vaccine and one dose of the Pfizer/BioNTech vaccine, which already has authorization in the UK. The Guardian adds that if the SARS-CoV-2 vaccine from Moderna receives authorization, it too will be included in the trial.

Kate Bingham, outgoing chair of the UK's vaccine taskforce, says the concept is known as a heterologous prime-boost. "It means mix and matching vaccines," she says.

The Guardian adds that "the idea is to combine them, in whichever order, to help the immune system respond more powerfully to SARS-CoV-2."

The Scan

Pig Organ Transplants Considered

The Wall Street Journal reports that the US Food and Drug Administration may soon allow clinical trials that involve transplanting pig organs into humans.

'Poo-Bank' Proposal

Harvard Medical School researchers suggest people should bank stool samples when they are young to transplant when they later develop age-related diseases.

Spurred to Develop Again

New Scientist reports that researchers may have uncovered why about 60 percent of in vitro fertilization embryos stop developing.

Science Papers Examine Breast Milk Cell Populations, Cerebral Cortex Cellular Diversity, Micronesia Population History

In Science this week: unique cell populations found within breast milk, 100 transcriptionally distinct cell populations uncovered in the cerebral cortex, and more.