Skip to main content
Premium Trial:

Request an Annual Quote

What's Next for NGS?

The PHG Foundation's Caroline Wright and her colleagues discuss the next steps for whole-genome sequencing in the clinic and make "specific recommendations for prompt and effective adoption within the UK National Health Service" in a new report. Funded by the foundation and with support from Illumina, Wright and her colleagues examined how advances in whole-genome sequencing and bioinformatic analysis pipelines show potential for applications in diseases like cancer; the ethical, legal, and social implications of such applications; the economics of sequencing in a health-care setting; and present policy recommendations. In a sign of the times, the PHG Foundation group added the following disclaimer to its report, released this week:

This report is accurate as of September 2011, but readers should be aware that genome sequencing technology and applications will continue to develop rapidly from this point.
The Scan

New Study Highlights Role of Genetics in ADHD

Researchers report in Nature Genetics on differences in genetic architecture between ADHD affecting children versus ADHD that persists into adulthood or is diagnosed in adults.

Study Highlights Pitfall of Large Gene Panels in Clinical Genomic Analysis

An analysis in Genetics in Medicine finds that as gene panels get larger, there is an increased chance of uncovering benign candidate variants.

Single-Cell Atlas of Drosophila Embryogenesis

A new paper in Science presents a single-cell atlas of fruit fly embryonic development over time.

Phage Cocktail Holds Promise for IBD

Researchers uncovered a combination phage therapy that targets Klebsiella pneumonia strains among individuals experiencing inflammatory bowel disease flare ups, as they report in Cell.