This Week in NEJM

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In NEJM this week, Schrappe et al. report on outcomes for children and adolescents with acute lymphoblastic leukemia, who suffer a failure of remission-induction therapy. The team identified induction failure by the persistence of leukemic blasts in blood, bone marrow, or any extramedullary site after treatment in 1,041 patients up to 18 years old.

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