In NEJM this week, researchers in the US and Europe report on the effects of MEK inhibitors on the survival of patients with BRAF-mutated melanoma. The team randomly assigned 322 patients with BRAF V600E or V600K metastatic melanoma to receive either the oral selective MEK inhibitor trametinib, or chemotherapy.

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In Science this week: swapping yeast genes with human orthologs to study conservation of function, and more.

Hong Kong is using DNA phenotyping to shame litterers.

A study appearing in Cell suggests some metastatic castration-resistant prostate cancer patients could benefit from PARP inhibitor therapy.

NIH's Francis Collins writes that scientific advances are poised to help populations all over the world, but more scientists are needed to keep the momentum.