This Week in Lancet Oncology

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In Lancet Oncology this week, researchers in the US and Belgium report the results of a phase II trial of ipilimumab for the treatment of patients with advanced melanoma that has metastasized to the brain. The team assigned 72 melanoma patients with brain metastases — 51 of whom were neurologically asymptomatic and were not receiving corticosteroid treatment and 21 of whom were symptomatic and on a stable dose of corticosteroids — to receive ipilimumab therapy.

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In Nature this week: omic analysis of permafrost microbes, hookworm genome, and more.

Biologists turn to environmental DNA sampling to determine whether elusive or invasive species are shedding DNA in a given area.

Rob Knight writes at Scientific American that microbiome studies are about to break out of the laboratory.

Harold Varmus, the director of the National Cancer Institute, has announced that he is stepping down after nearly five years.