In Clinical Cancer Research this week, researchers at the University of Michigan Comprehensive Cancer Center report that upregulated JAG1 in adrenocortical carcinoma enhances proliferation of cancer cells in adrenocortical Carcinoma. The team found that JAG1 expression is upregulated in most adrenocortical carcinoma cell lines, and that it enhances cell proliferation through the activation of canonical Notch signaling.

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In PNAS this week: co-evolutionary signatures of insect hosts and bacterial symbionts, distinct transcript isoforms of high-grade ovarian cancer, and more.

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