This Week in Cancer Cell

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In Cancer Cell this week, a team led by researchers at MD Anderson Cancer Center report that p53-mediated senescence in breast cancer cells impairs the apoptotic response to chemotherapy. The team shows that mammary tumors with mutant p53 exhibit a "superior clinical response" compared to tumors with wild-type p53 — p53 mutant tumors treated with doxorubicin continued to proliferate, leading to abnormal mitosis, whereas wild-type p53 tumors arrested when treated with doxorubicin.

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An Australian study of personalized medicine has run into problems as it recruits patients.

In Science this week: mtDNA analysis give glimpse into decline of Neanderthals in Europe, and more.

The University of Arizona's Raina Maier writes that an understanding of the Earth's microbiome is needed.

The proposed Canadian budget emphasizes partnerships with industry, Nature News reports.