This Week in Cancer Cell | GenomeWeb

This Week in Cancer Cell


In Cancer Cell this week, a team led by researchers at MD Anderson Cancer Center report that p53-mediated senescence in breast cancer cells impairs the apoptotic response to chemotherapy. The team shows that mammary tumors with mutant p53 exhibit a "superior clinical response" compared to tumors with wild-type p53 — p53 mutant tumors treated with doxorubicin continued to proliferate, leading to abnormal mitosis, whereas wild-type p53 tumors arrested when treated with doxorubicin.

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In Nature this week: genomic analysis of 200 bird species, and more.

The Australian High Court rules that isolated genetic material cannot be patented.

The startup incubator Y Combinator is launching a nonprofit research lab.

In Genome Research this week: vervet genome, tandem repeats affect gene expression in great apes, and more.