In the British Journal of Cancer this week, researchers in the UK report that NT5E is epigenetically regulated in patients with malignant melanoma. The team analyzed the expression and regulation of NT5E in malignant melanoma cell lines, and in samples of primary and metastatic melanomas, and found that the gene is subject to epigenetic regulation in the disease. It is down-regulated by methylation-dependent transcriptional silencing in several cell lines, the team writes.

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In Science this week: the Human Silencing Hub protein complex, and more.

Heads of various research funding agencies discuss how to encourage scientific breakthroughs, ScienceInsider reports.

The Kansas City Star examines issues surrounding newborn genome sequencing.

Researchers say their Research Resource Identifier citation format is catching on, Nature News reports.