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Ultima Genomics

In Brief This Week: Meridian Bioscience, SQI Diagnostics, Applied DNA, Abbott, Danaher, More

News items for the week of Feb. 6, 2023.

AGBT: cfDNA Methylation Profiling Shows Promise as Blood Biomarker for Congestive Heart Failure

Presenting at AGBT, Hebrew University of Jerusalem researchers showed plasma cfDNA methylation signals can potentially become biomarkers for cardiac diseases.

NY Genome Center Team Harnesses Ultima Genomics Platform for High-Sensitivity ctDNA Sequencing
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Taking advantage of the new platform's low sequencing cost, the researchers sequenced cell-free circulating DNA (ccfDNA) in plasma at high depth for sensitive cancer monitoring.

JP Morgan Healthcare Conference, Day 1: Guardant Health, Exact Sciences, Bruker, 10x Genomics, More

Highlights from the first day included Exact Sciences' profitability forecast, an update on QuidelOrtho's integration, and Guardant Health's "quantum leap forward" with its "smart" liquid biopsy platform.

Sequencing Instrument Launches in 2022 Portend Heated Competition
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Customers are feeling euphoric, but sequencing firms face a number of headaches including competitive pressure and global macroeconomic concerns.

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Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.