UK Biobank
UK Biobank Plasma Proteomic, Genetic Study Uncovers Asthma Biomarkers, Drug Targets
Researchers from Genentech focused in on blood plasma proteins linked to asthma, including potential disease biomarkers and drug targets.
Potential Treatment Target Genes Found in Genomic Study of Bipolar Disorder
Researchers flagged genes containing rare, loss-of-function mutations in bipolar disorder using genome sequences from hundreds of thousands of individuals.
Brain Aging GWAS Informs Drug Repurposing Effort
Researchers used Mendelian randomization and quantitative trait locus analyses to search for targets of potential drugs that could slow down brain aging.
Cancer Susceptibility Rare Coding Variants Uncovered in UK Biobank Analysis
Researchers used exome sequences from 450,000 UKB participants to find rare cancer susceptibility contributors, pointing to cancer types with shared genetic risk.
Heart Failure GWAS Leads to New Risk Loci, Disease Subtype Insights
Researchers uncovered genetic contributors to heart failure, revealing multiorgan features and a reduced ejection fraction subtype that is particularly impacted by genetics.