immune response
Population Differences in SARS-CoV-2 Response Uncovered in Single-Cell Sequencing Study
A single-cell analysis suggests immune cell proportions and blood cell expression patterns vary between individuals, across populations, and with exposure to different viruses.
COVID-19 Protection Provided by HLA Genetic Variant, Study Suggests
Using data from bone marrow registry participants, researchers found an HLA variant linked to symptom-free SARS-CoV-2 infection and better immune cell responses.
Transcriptomics Unravels Role of Interferon Receptors in Down's Syndrome
The findings of a transcriptome analysis of blood from 304 individuals with Down's syndrome and 96 controls have implications for therapeutic development.
The five-year, EU-funded project, called MensEndoDiag, will explore the use of menstrual blood as a sample type.
Wellcome Sanger's Dandelion Pipeline Updated for Single-Cell Adaptive Immune Receptor Analysis
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The Dandelion bioinformatics method now includes T-cell receptor-based "pseudotime trajectory analysis" to support better understanding of single-cell lymphocyte biology.