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Personalis, Ono Pharmaceutical, Japan National Cancer Center Partner on Opdivo Rectal Cancer Trial

In the multicenter VOLTAGE-2 trial, investigators will compare results of the company's tests with standard-of-care measures of drug response.

Cofactor Quickly Moving Immunotherapy Predictive Test to Market With Data From Intermountain Spinout
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Culmination Bio's 4.5 million biospecimens and longitudinal omics and clinical data may help Cofactor rapidly advance the OncoPrism assay into multiple cancer types.

Culmination Bio, Cofactor Genomics Team up on Study to Advance Immunotherapy Response Test

Culmination will give Cofactor access to over 4.5 million biological samples to advance the firm's assay to predict immunotherapy response in 11 cancer types.

Servier, Qiagen to Develop PCR-Based Companion Diagnostic to Identify IDH1-Mutant Leukemia

Qiagen will develop a real-time PCR-based in vitro diagnostic to identify patients eligible for Servier's Tibsovo and investigational IDH1-targeted agents.

Earlier CYP2C19 Testing Linked With Lower Risk of Cardiovascular Events, Study Shows
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In multiple presentations, researchers at ACC/WCC's annual meeting explored the impact of genotyping cardiac patients within a week of starting dual anti-platelet therapy.

Nov 17, 2022

Biomarker Predicts Immunotherapy Benefit in Head and Neck Cancer but Commercial Path Unclear
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Oct 4, 2022

Personalis, Duke University, Olink Collaborate on Immunotherapy Markers in Gastric Cancer

Sep 11, 2022

Repeat Biomarker Testing Informs Next Steps for Treatment-Resistant EGFR-Mutant NSCLC Patients
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Jul 12, 2022

NCCN Publishes First Guidelines for Pediatric Brain Cancer, Recommends Broad NGS Profiling

Jun 22, 2022

Agendia Building Validation Data on ImPrint for Guiding Neoadjuvant Immunotherapy in Breast Cancer
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Jun 9, 2022

Tempus, Lilly Ink Partnership to Offer No-Cost NGS for Advanced NSCLC Patients

Mar 11, 2022

FDA Approves Lynparza as Adjuvant Therapy With Myriad Genetics CDx for BRCA-Mutated Breast Cancer

Feb 24, 2022

Amoy Diagnostics, Pierre Fabre Collaborate to Develop CDx in China

Feb 22, 2022

FDA Approves Foundation Medicine Test as CDx for Merck's Keytruda to Identify MSI-H Solid Tumors

Feb 9, 2022

Foundation Medicine, Eli Lilly Ink CDx Development Deal for Retevmo

Dec 8, 2021

Foundation Medicine Test Nabs FDA Approval as CDx for BRAF Inhibitor Therapeutics for Melanoma

Nov 11, 2021

Breast Cancer Study Shows Number of Mutated PIK3CA Alleles Affects Tumor Aggressiveness

Oct 1, 2021

UK Researchers Show Cytotoxic T-Cell Level Predicts Melanoma Immunotherapy Response

Sep 16, 2021

Molecular Clonal Tracking Method Captures Lung Cancer Treatment Response, Resistance Features

Sep 7, 2021

Illumina, Merck Partner to Advance Homologous Recombination Deficiency CDx, Research Assay

Aug 17, 2021

Amoy Diagnostics CDx Gets Japanese Approval to ID NSCLC Patients Eligible for Tepmetko

Jul 21, 2021

Sequencing-Based Assessment of CYP2D6 Could Improve Prediction of Drug Response
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Jul 16, 2021

FDA Approves Foundation Medicine's Liquid Biopsy Test as CDx for Novartis' Tabrecta in NSCLC

Jul 1, 2021

FDA Approves FoundationOne CDx for Takeda's ALK-Inhibitor

Jun 14, 2021

Genecast to Evaluate Liquid Biopsy EGFR Mutation Test in Early-Stage Non-Small Cell Lung Cancer

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The Scan

Open Pediatric Brain Tumor Atlas Team Introduces Genomic Data Collection, Analytical Tools

A study in Cell Genomics outlines open-source methods being used to analyze and translate whole-genome, exome, and RNA sequence data from the Pediatric Brain Tumor Atlas.

Neurological Outcomes Linked to Innate Immune Features After Cardiac Arrest

Researchers reporting in Med dig into immune features found a few hours after cardiac arrest that correspond with neurological outcomes.

Mouse Study Finds Circadian Rhythm-Related Gene Expression Changes Linked to Sleep Apnea

A paper in PLOS Biology reveals tissue-specific circadian rhythm and gene expression patterns in an intermittent hypoxia-based mouse model of obstructive sleep apnea.

Polygenic Risk Score to Predict Preeclampsia, Gestational Hypertension in Pregnant Women

Researchers in Nature Medicine provide new mechanistic insights into the development of hypertensive disorders of pregnancy, which may help develop therapeutics.