Drug Names Foundation Medicine Test Nabs FDA Approval as CDx for BRAF Inhibitor Therapeutics for Melanoma FoundationOneCDx will also automatically be a companion diagnostic for future BRAF inhibitors approved by the FDA that target specific BRAF mutations. Breast Cancer Study Shows Number of Mutated PIK3CA Alleles Affects Tumor Aggressiveness Studies in breast tumors revealed a "biphasic" relationship between mutant PIK3CA allele dosage and stem cell-like features as well as aggressiveness. UK Researchers Show Cytotoxic T-Cell Level Predicts Melanoma Immunotherapy Response A Science Immunology paper details how patients with more cytotoxic effector T cells in peripheral blood at baseline respond better to checkpoint inhibitors. Molecular Clonal Tracking Method Captures Lung Cancer Treatment Response, Resistance Features Using a single-cell sequencing and clonal fitness mapping method, researchers compared EGFR-mutant lung cancer cell responses to EGFR inhibition or targeted protein degradation. Illumina, Merck Partner to Advance Homologous Recombination Deficiency CDx, Research Assay Under the terms of the deal, Illumina will develop a new HRD CDx for the EU and UK markets and a research-use only HRD assay that will be add-on content for its TSO 500 panel. Aug 17, 2021 Amoy Diagnostics CDx Gets Japanese Approval to ID NSCLC Patients Eligible for Tepmetko Jul 21, 2021 Sequencing-Based Assessment of CYP2D6 Could Improve Prediction of Drug Response Premium Jul 16, 2021 FDA Approves Foundation Medicine's Liquid Biopsy Test as CDx for Novartis' Tabrecta in NSCLC Jul 1, 2021 FDA Approves FoundationOne CDx for Takeda's ALK-Inhibitor Jun 14, 2021 Genecast to Evaluate Liquid Biopsy EGFR Mutation Test in Early-Stage Non-Small Cell Lung Cancer Jun 7, 2021 Lynparza Benefit in Early BRCA-Mutated Breast Cancer Reignites Universal Genetic Testing Discussion Premium May 26, 2021 23andMe Begins Reporting PGx Variants With Drug Info Under Recent FDA Clearance Premium May 7, 2021 Breast Cancer Immunotherapy Response Markers Emerge From Single-Cell Sequencing Study Apr 12, 2021 Oncocyte AACR Data Expands Potential Applications for Immunotherapy Response Predictor Apr 6, 2021 Uterine Leiomyosarcoma Sequences Point to Potentially Targetable Somatic Mutations Mar 18, 2021 Oncocyte Details New Expansions Plans With Growing Portfolio of Acquired Tests Premium Mar 17, 2021 Meta-Analysis Supports Pharmacogenomic Testing Prior to Anti-Platelet Therapy Mar 16, 2021 Cofactor Genomics Cements Clinical Diagnostic Plans as Immunotherapy Prediction Data Builds Premium Feb 26, 2021 Natera Launches Tumor Genomic Profiling Assay, Expects Reproductive Health to Break Even This Year Premium Feb 18, 2021 MSK Study Underscores Need to Validate Cancer-Specific Tumor Mutational Burden Cutoffs Premium Feb 16, 2021 Circulating Tumor DNA Provides Prognostic Clues in Advanced BRAF-Mutated Melanoma Cases Feb 8, 2021 Sophia Genetics, Spanish Lung Cancer Group Team up to Predict Lung Cancer Treatment Response Jan 28, 2021 OmniSeq, UPMC Partner on Immunotherapy Trial Matching for Head and Neck Cancer Jan 26, 2021 Researchers ID Four Small Cell Lung Cancer Subtypes, Suggest Future Treatment Implications Premium Jan 20, 2021 Biotheranostics' Breast Cancer Index Included in Latest NCCN Guidelines Load More Breaking News Pediatric Cardiomyopathy Exome Sequencing Study Suggests More Disease Genes to be Found People in the News: New Appointments at Helix, Pacific Biosciences, SomaLogic, More New Products Posted to GenomeWeb: Amoy Diagnostics, Akoya Biosciences, Congenica, Lucence In Brief This Week: BGI, Gencove, Cepheid, Biocartis, Biognosys, Co-Diagnostics, More Florida Lab Owner Pleads Guilty to $6.9M COVID-19 False Billing Scheme Pacific Biosciences Outlines Progress on Short-Read Sequencing at JPM, Partners With Canexia Health The Scan Close Panel Vote on Califf Nomination The New York Times reports there was a close committee vote to advance the nomination of Robert Califf to lead the US Food and Drug Administration to the full Senate. Task Force Reports on Scientific Integrity Nature News writes that that a new task force report recommends that the US establish a cross-agency scientific integrity council. Across the Hall Genetic testing, closed-circuit cameras, and more show how a traveler, without any contact, infected others at a New Zealand quarantine facility, CNN reports. Science Paper Examines Influence of Chromatin Modifications on Obsessive-Compulsive Disorder In Science this week: genes regulating chromatin modification may contribute to OCD risk.