clonal hematopoiesis
Low-Coverage WGS Study Reveals Perils Faced by 'Hero' Transplanted Blood Stem Cells
Hematopoietic stem cells transplanted from younger donors in their 20s and 30s survive more often than those from older donors, the study found.
Clonal Expansion Limited in Stem Cell Transplant Recipients, Even After Long Time
Researchers used ultra-sensitive duplex sequencing to compare clonal hematopoiesis and myeloid cancer-related mutation patterns in transplant donors and recipients over time.
Telomere Length Linked to Rare Variants, Clonal Hematopoiesis Genes
Using data for almost 490,400 UK Biobank participants, researchers analyzed variants and genes associated with telomere length.
Clinical Trial Exome Sequencing Shows No Link Between Clonal Hematopoiesis, Repeat Coronary Events
Researchers saw a relationship between incident coronary events and an age-related form of blood stem cell expansion, without ties to subsequent events.
In UK Biobank data, researchers found that clonal hematopoiesis of indeterminate potential exacerbates the impact of air pollution in non-smokers with lung cancer.