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antimicrobial resistance

Day Zero Diagnostics Aiming to Bring Whole-Genome Sequencing Pathogen ID/AST to Clinical Labs
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The firm intends to use new funding to move its platform into the clinical trial stage in the pursuit of an FDA-regulated IVD product.

Curetis, FIND Extend Antimicrobial Resistance Research Collaboration

The extended partnership covers the development of an AMR assay, a cartridge for the Unyvero A30 platform, and a software plug-in.

Rapid Pathogen ID/AST Market Begins to Recover Post-COVID as Drug-Resistant Infections Spike
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Although bacterial and fungal drug resistance rates increased during the pandemic, a heavy focus on COVID testing has slowed adoption of novel ID/AST technologies.

Sepsis Testing Startup DeepUll Raises €13M

The diagnostics firm is developing a culture-free system for guiding treatment selection for sepsis patients.

NIST Analysis Discovers Sample Processing Bias in Metagenomic Wastewater Surveillance
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The finding underscores the need to standardize sampling protocols to minimize biases in wastewater antimicrobial resistance monitoring.

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The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.