COLD SPRING HARBOR, NY (GenomeWeb) – By relying on the Hi-C approach to map interactions between chromatin regions, researchers have been able to assemble de novo mammalian genomes for less than $1,000.

Olga Dudchenko, a postdoc in Erez Lieberman Aiden's lab at the Baylor College of Medicine, said during her talk at the Biology of Genomes meeting here that other approaches have been used to align a genome for the same cost. However, she noted that those methods depend upon reference genomes.

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