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Illumina Stock Downgraded to 'In-Line' by Evercore ISI

The investment banking firm has lowered its rating for shares of the sequencing giant, but raised its price target to $340 from $330.

Circular Cell-Free DNA in Plasma of Pregnant Women May Serve as Novel Biomarker

A team led by researchers at the Chinese University of Hong Kong found that extrachromosomal circular DNA of fetal origin is smaller than that of maternal origin.

Circulating Tumor DNA Methylation Profiles May Aid in Colorectal Cancer Early Diagnosis, Prognosis

A Sun-Yat Sen University Cancer Center-led team found circulating tumor DNA methylation patterns could detect colorectal cancer among asymptomatic individuals.

Evercore ISI Upgrades PerkinElmer, Downgrades Hologic

The investment bank gave PerkinElmer an Outperform rating with a $114 stock price target and Hologic an In Line rating with a $55 stock price target.

PHR Startup Ciitizen Sees Hope in Aggregating Genotype, Phenotype Data for Patients
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The fledgling company, started as a promise to the founder's dying sister, is trying to succeed in a consumer niche where so many others have failed.

In 2019, Gains in Throughput Position Proteomics for Future Clinical Impact
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With new instruments and workflows able to quantify thousands of proteins in as little as five minutes, 2019 was the year proteomics cracked its throughput problem.
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Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.

Melanoma Linked to Altered Gut Microbes in Case-Control Study

A JAMA Dermatology paper points to melanoma-related gut microbial community shifts, along with differences in gut microbiomes of early- or late-stage melanoma cases.

Study Considers Genetic, Social Contributors to Mortality in Black Breast Cancer Survivors

A JAMA Network Open study suggests African ancestry has stronger ties to tumor subtype and aggressiveness than mortality risk, which was influenced by socioeconomic factors.
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Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.

Melanoma Linked to Altered Gut Microbes in Case-Control Study

A JAMA Dermatology paper points to melanoma-related gut microbial community shifts, along with differences in gut microbiomes of early- or late-stage melanoma cases.