x-ray crystallography

Understanding how the enzyme positions the target DNA for cleavage could lead to new engineered Cas9 variants that increase efficiency and specificity.

Researchers get a clear image of the DROSHA protein and gain a better understanding of the Microprocessor complex involved in miRNA biogenesis. 

NEW YORK (GenomeWeb) – Three UK science funding agencies have jointly contributed £5.6 million ($9.4 million) toward the European X-ray Free Electron Lasers (XFEL) project, a facility currently under construction in Hamburg, Germany that will provide scientists with access to advanced crystallogr

NEW YORK (GenomeWeb News) – The National Science Foundation has awarded $25 million to fund a new center at the University of Buffalo that will use X-ray bioimaging technologies to analyze molecular targets for their use as therapeutic drugs, NSF said yesterday.

NEW YORK (GenomeWeb News) – For a protein that has been around for about 4 billion years, thioredoxin has gone through remarkably few changes, researchers from the University of Granada in Spain reported today in the journal Stucture.

NEW YORK (GenomeWeb News) – Scripps Research Institute has received a three-year, $2.7 million grant from the National Institute of General Medical Sciences to study the structural rules governing a class of proteins that help regulate cellular functions, such as reproduction, development, and me

Proteros will provide X-ray structural analysis of protein compound complexes for specific targets to support Rigel's drug discovery program.

Under a deal announced today, Proteros will provide structures from its Gallery Structure catalogue of ready-to-use proteins for X-ray structure analysis of protein-ligand complexes, as well as gene-to-structure projects for novel biological targets.

The firm will provide the foundation with structure-based drug discovery services.

The firms achieved a second milestone in their drug discovery pact, which utilizes Emerald's X-ray crystallography platform.

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The Washington Post reports on a Federal Bureau of Investigation plan to place rapid DNA analyzers at booking stations around the country.

In an editorial, officials from scientific societies in the US and China call for the international community to develop criteria and standards for human germline editing.

The US National Institutes of Health is to review studies that have received private support for conflicts of interest, according to the New York Times.

In Science this week: the PsychENCODE Consortium reports on the molecular mechanisms of neuropsychiatric disorders, and more.