x-ray crystallography

Understanding how the enzyme positions the target DNA for cleavage could lead to new engineered Cas9 variants that increase efficiency and specificity.

Researchers get a clear image of the DROSHA protein and gain a better understanding of the Microprocessor complex involved in miRNA biogenesis. 

NEW YORK (GenomeWeb) – Three UK science funding agencies have jointly contributed £5.6 million ($9.4 million) toward the European X-ray Free Electron Lasers (XFEL) project, a facility currently under construction in Hamburg, Germany that will provide scientists with access to advanced crystallogr

NEW YORK (GenomeWeb News) – The National Science Foundation has awarded $25 million to fund a new center at the University of Buffalo that will use X-ray bioimaging technologies to analyze molecular targets for their use as therapeutic drugs, NSF said yesterday.

NEW YORK (GenomeWeb News) – For a protein that has been around for about 4 billion years, thioredoxin has gone through remarkably few changes, researchers from the University of Granada in Spain reported today in the journal Stucture.

NEW YORK (GenomeWeb News) – Scripps Research Institute has received a three-year, $2.7 million grant from the National Institute of General Medical Sciences to study the structural rules governing a class of proteins that help regulate cellular functions, such as reproduction, development, and me

Proteros will provide X-ray structural analysis of protein compound complexes for specific targets to support Rigel's drug discovery program.

Under a deal announced today, Proteros will provide structures from its Gallery Structure catalogue of ready-to-use proteins for X-ray structure analysis of protein-ligand complexes, as well as gene-to-structure projects for novel biological targets.

The firm will provide the foundation with structure-based drug discovery services.

The firms achieved a second milestone in their drug discovery pact, which utilizes Emerald's X-ray crystallography platform.

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A fire at a Manchester hospital may have destroyed lab equipment and data, the Guardian reports.

Researchers generate a genetic database from skeletal remains from the 1845 Franklin Expedition to the Arctic, Live Science reports.

Researchers in China have begun another trial using CRISPR/Cas9 approaches in cancer patients, according to the Wall Street Journal.

In Science this week: human DNA found in sediments from archeological sites lacking bones, and more.