x-ray crystallography

Understanding how the enzyme positions the target DNA for cleavage could lead to new engineered Cas9 variants that increase efficiency and specificity.

Researchers get a clear image of the DROSHA protein and gain a better understanding of the Microprocessor complex involved in miRNA biogenesis. 

NEW YORK (GenomeWeb) – Three UK science funding agencies have jointly contributed £5.6 million ($9.4 million) toward the European X-ray Free Electron Lasers (XFEL) project, a facility currently under construction in Hamburg, Germany that will provide scientists with access to advanced crystallogr

NEW YORK (GenomeWeb News) – The National Science Foundation has awarded $25 million to fund a new center at the University of Buffalo that will use X-ray bioimaging technologies to analyze molecular targets for their use as therapeutic drugs, NSF said yesterday.

NEW YORK (GenomeWeb News) – For a protein that has been around for about 4 billion years, thioredoxin has gone through remarkably few changes, researchers from the University of Granada in Spain reported today in the journal Stucture.

NEW YORK (GenomeWeb News) – Scripps Research Institute has received a three-year, $2.7 million grant from the National Institute of General Medical Sciences to study the structural rules governing a class of proteins that help regulate cellular functions, such as reproduction, development, and me

Proteros will provide X-ray structural analysis of protein compound complexes for specific targets to support Rigel's drug discovery program.

Under a deal announced today, Proteros will provide structures from its Gallery Structure catalogue of ready-to-use proteins for X-ray structure analysis of protein-ligand complexes, as well as gene-to-structure projects for novel biological targets.

The firm will provide the foundation with structure-based drug discovery services.

The firms achieved a second milestone in their drug discovery pact, which utilizes Emerald's X-ray crystallography platform.

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What happens to scientific papers when certain journals are no longer published? Some scientists are trying to make sure they don't disappear forever.

A study in Microbiome finds that heavy drinkers have an unhealthy mix of bacteria in their mouths.

Doctors and patients are still trying to figure out what role at-home genetic testing should play in healthcare, Newsweek says.

In Genome Research this week, mismatch repair deficiency in C. elegans, retracing transcriptions start site evolution in the human genome, and more.