whole-genome sequencing Analysis of Multi-Ancestry Cohort Uncovers Dozens of Genes Linked to Blood Lipid Levels The researchers conducted gene-based association testing of blood lipid levels in more than 170,000 individuals of various ancestral backgrounds. Seven Bridges Genomics to Foster Partnerships Between Health Systems, Pharmas With New Subsidiary Premium The Unified Patient Network expects pharmaceutical companies to sponsor whole-genome sequencing for patients from health systems for research and clinical purposes. Researchers ID Genomic Signature to Risk Stratify Patients With Precancerous Breast Lesions In the study, presented at SABCS, researchers developed an 812-gene signature that could identify which patients with ductal carcinoma in situ need aggressive treatment. Variant Identified in Amish Population Appears to Protect From Cardiovascular Disease A rare missense variant in the enzyme-coding gene B4GALT1 is linked to lower coronary artery disease risk and reduced blood LDL cholesterol levels. Fabric Genomics Algorithm Validated for Rare Disease Diagnosis in Two New Studies Premium The firm worked with Genomics England and Rady Children's Institute to collect data about the efficacy of its AI-based genetic test software. Nov 23, 2021 Genome Sequencing, EHR Machine Learning Method Detects Unnoticed Hospital Outbreaks Premium Nov 19, 2021 Evolution of Dengue Virus Antigens Reflected in Outbreaks in Thailand Nov 18, 2021 Ancient DNA Details Bronze Age Population Shifts in Southern Iberia Nov 17, 2021 Multiple Myeloma Patient Similarity Network Reveals Prognostically Informative Subgroups Nov 17, 2021 Team Shares Chinese Genome Resource, Population Reference Panel Nov 16, 2021 Illumina, Genetic Alliance Launch $120M Global Whole-Genome Sequencing Program Nov 12, 2021 Childhood Brain Tumors in Crosshairs of New CHOP-led Sequencing Biobank Effort Premium Nov 11, 2021 Whole-Genome Sequencing Shines for Rare Disease Diagnosis in 100K Genomes Pilot Study Nov 10, 2021 Spread of Transeurasian Languages Linked to Agricultural Groups in Interdisciplinary Study Nov 3, 2021 Genomic Answers for Kids Team Releases Thousands of Genomes to Gain Insights Into Rare Diseases Premium Oct 27, 2021 Relationship of Sitting Bull Descendant Verified With Ancient DNA From Lock of Hair Oct 27, 2021 Illumina, Israel Ministry of Health to Pilot Genome Sequencing for Diagnosing Critically Ill Infants Oct 26, 2021 Multiomic Study Identifies Drivers of Severe COVID-19 in Patients Under 50 Without Comorbidities Oct 25, 2021 UK Biobank WGS Consortium Describes 150K Genome Dataset at ASHG, Sets Sights on 500K Premium Oct 22, 2021 SUPER Psychosis Study Presented at ASHG Digs Into Relationships of Rare Variants, Phenotypes Oct 20, 2021 Rady Children's Team Presents Genomic Medicine Management Tool at ASHG Oct 20, 2021 Genomic Studies Presented at ASHG Explore Malaria Responses in West African Children Oct 19, 2021 Cystic Fibrosis Sinus Infections Involve Microbes With Shifting Evolution Patterns Oct 14, 2021 SARS-CoV-2 Genomes Reveal Dynamics of England's Alpha, Delta Variant Surges Oct 13, 2021 Chronic Liver Disease Genome Sequences Point to Recurrent Mutations in Metabolic Genes Load More Breaking News Centogene Strikes Rare Disease Target Discovery Deal With Insilico Medicine Dilated Cardiomyopathy Gene Mutations Point to Possible Therapeutic Strategy Ginkgo Bioworks Acquires Massachusetts COVID-19 Testing Firm Mainz Biomed Taps DCN Dx to Aid European Study of Enhanced ColoAlert Assay Parse Biosciences Partners With Research Instruments for Southeast Asia Distribution Thermo Fisher, Oncocyte Ink Development, Comarketing Deal for Cancer IVDs The Scan And a Fourth? A fourth dose of the Pfizer-BioNTech SARS-CoV-2 vaccine in an Israeli study increased antibody levels but did not prevent Omicron variant infections, according to the Financial Times. For Better Science Software A virtual institute funded by former Google CEO Eric Schmidt's philanthropy aims to lure software engineers to academia, Science reports. Recommendation Explanations The New York Times writes that the US Centers for Disease Control and Prevention is straining to both make and explain decisions based on limited information. Genome Research Papers on De Novo Mutation Rates, Polyploid Genotyping, Oncogene Epigenomic Translocation In Genome Research this week: de novo mutations rates in hemoglobin subunits, analysis of variant calling methods for polyploid plants, and more.