whole-genome sequencing

Africanized honey bee

Researchers identified a genetically distinct cluster of gentle Africanized honeybees in Puerto Rico, which appear to have undergone selection in recent years.

A tumor sequencing study suggests the retention or deletion of interstitial genes within the TMPRSS2-ERG gene fusion may coincide with prostate cancer progression.

By sequencing Vibrio cholerae isolates from Africa and Latin America, investigators got a look at the lineages leading to outbreaks over several decades.

The company, which first signed on to provide services to the VA's Million Veteran Program in 2013, will provide the department with 34,000 more genomes.

LifeOmic, founded less than a year ago, expects omic data sets to become as clinically relevant as diagnostic medical imaging.

As of this week, the project had sequenced 39,500 genomes and returned reports for about 3,000 rare disease families and more than 600 cancer patients.

This Week in PLOS

In PLOS this week: circular RNAs in infantile hemangiomas, pathogenic mutations in Alzheimer's disease, and more.

An analysis of new and available liver cancer genomes led to 10 mutational signatures and six structural rearrangement signatures in hepatocellular carcinoma.

Batang Toru orangutan

Using genome sequencing, phylogenomics, morphological analyses, and more, investigators defined a rare new orangutan species dubbed Pongo tapanuliensis.

This Week in PLOS

In PLOS this week: plague patterns in Kyrgyzstan, trypanosomiasis susceptibility variants, and more.

Pages

Researchers test gene therapy targeting a different cancer protein in a new trial, the New York Times reports.

Pennsylvania State University researchers found that salivary microRNAs could predict which kids would have longer concussion symptoms, according to NPR.

The Associated Press reports Alex Azar, the new Department of Health and Human Services secretary nominee, made millions of dollars as a pharmaceutical executive.

In PNAS this week: immune profiling of breast cancer, transposable element patterns in rice, and more.