whole-genome sequencing
Investigational Cancer Drug Deemed Highly Mutagenic in Cell Line Sequencing Study
Using whole-genome sequencing on drug-exposed cell lines, researchers saw high mutation rates in control cell lines intermittently treated with a compound called CX-5461.
The resource contains Illumina whole-genome sequencing data from UK Biobank participants and is available to approved researchers worldwide.
Comparison of 239 Primate Genomes Reveals Conserved Regulatory Sequences
By aligning and comparing whole-genome sequences for 239 species, researchers identified regulatory elements that have become constrained specifically in primates.
Fetal Exome Sequencing Studies Point to Noninvasive Prenatal Screening Applications
New research suggests trio exome sequencing on parental DNA samples and cell-free DNA from maternal plasma can successfully uncover clinically relevant fetal variants.
Germany to Test Genomics-Based Precision Medicine for Cancer, Rare Disease in National Pilot Project
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With reimbursement from public health insurance, the "model project" will run for at least five years and examine the utility of genomic sequencing for advanced cancer and rare disease patients.