whole-genome sequencing

Researchers identified variants in the germline that appear to influence DNA methylation levels in prostate cancer tumors or in precancerous tissues.

Tempus Labs researchers said they could match more than 40 percent of patients to a targeted treatment and 77 percent of patients to a relevant clinical trial.

A report from the NSIGHT2 trial compares the diagnostic and analytical performance of clinical whole-genome and exome sequencing on an infant cohort.

Researchers identified Streptococcus pyogenes isolates from a lineage dubbed M1UK that are predicted to produce higher-than-usual levels of a scarlet fever-associated toxin.

The project is funded with £50 million from the UK government, £50 million from the Wellcome Trust, and £100 million from four pharmaceutical firms.

The Long Life Family Study has enrolled 4,953 participants in 539 pedigrees in the US and Denmark that are enriched for exceptional longevity.

Researchers saw representatives from at least three population clusters who died up to 1,000 years apart at the "enigmatic" site in the Indian Himalayas.

The clinic will offer comprehensive DNA sequencing, interpretation, and reporting of disease-associated genes for healthy adults and their children.