whole-genome sequencing

At least some variants associated with benign prostatic hyperplasia appeared to contribute to PSA levels in the blood, independent of prostate cancer.

Three studies encompassing dozens of ancient genomes are offering a closer look at complex historical population spread in North, Central, and South America.

Researchers trained a machine-learning model to predict animal reservoirs or insect vectors for dozens of "orphan" viruses with unknown natural sources.

Using biorepository strains, researchers from the J. Craig Venter Institute and elsewhere profiled Zika virus consensus sequences, variant patterns, and phylogenetics.

A common variant polygenic risk score, rare cancer risk gene mutations, and prior treatments each provide clues to breast cancer risk in childhood cancer survivors.

An Australian team has sequenced some 4,000 healthy individuals over 70 years old for the Medical Genome Reference Bank database.

The company reported $853 million in total revenues for the quarter, driven by growth across its sequencing and microarray products.

The team uncovered more than 200 sites in the human genome that were differentially methylated based on parent of origin, including areas linked to disease.

British genomics interpretation software vendor Congenica will help researchers analyze WGS and WES in search of a genetic cause for sudden unexpected death in epilepsy.

Researchers saw frequent somatic mutations in esophageal tissue from nine individuals, including mutations under positive selection in 14 oncogenes.

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Hundreds of scientists have signed a letter criticizing the open-access Plan S, ScienceInsider reports.

NPR speaks with Rep. Eddie Bernice Johnson (D-Texas) about the US House of Representatives science committee.

A start-up company aiming to match cancer patients to treatments closes after about six weeks, Stat News reports.

In PLOS this week: somatic mutation associations unearthed in thousands of cancer exomes, pathogen detection assay, and more.