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whole-genome sequencing

With single-cell genome sequencing, recombination assays, and other approaches in mouse cells, researchers identified factors affecting DNA crossover.

Molecular features in primary and recurrent glioblastomas indicated that key initiator mutations turned up years before diagnosis, often persisting in recurrent tumors.

A draft genome for the three-banded panther worm served as the foundation to untangle regulatory and chromatin accessibility changes triggered during regeneration.

Analyzing mutational signatures in cancer cell lines and xenografts, investigators identified mutagenic processes that do or don't remain active in vitro.

The assay monitors mutations across a patient's genome and matches them to mutations found in a patient's resected tumor and in DNA in the bloodstream.

The Personal Genome Sequencing Outcomes (PeopleSeq) Consortium surveyed more than 500 early adopters who underwent personal genome or exome sequencing.

The consortium plans to develop recommendations on the best practices for implementing clinical whole-genome sequencing for rare genetic disease diagnosis.

Researchers assembled a near chromosome-level genome for the cultivated octoploid strawberry, uncovering the plant's diploid progenitors and sub-genome interactions.

This Week in Nature

In Nature this week: protein-coding variants associated with body-fat distribution, and more.

Researchers used genomic, transcriptomic, and virulence data on thousands of Streptococcus pyogenes strains to identify features influencing infections.

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Researchers representing scientists and students of Chinese descent voice their concerns about recent US policies and rhetoric.

Wired reports that researchers have shown they could reprogram a DNA-based computer.

Researchers say increased diversity in genomic studies will benefit all, PBS NewsHour reports.

In Science this week: whole-genome sequencing of single sperm cells, and more.