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whole-genome sequencing

Researchers demonstrated the importance of integrating mutational and transcriptomic profiles to improve understanding of AML and MDS patients' prognosis.

In a Twitter message dated Dec. 4, the company said it is suspending its US operations for the time being "due to an unexpected adverse financing situation."

The government-backed project aims to better understand genetic diversity around the South Asian country while helping to inform clinical applications.

Using ancient DNA, researchers retraced ancestral diversity and human migrations through Rome and central Italy going back more than 10,000 years.

Researchers documented population structure, ancestry patterns, trait associations, and more with variants found in the genomes of more than 6,400 Ugandans.

With genome sequencing, investigators tracked down a sole stool donor carrying the same multi-drug resistant form of Escherichia coli found in two FMT recipients with bacteremia.

The program will likely only generate sequencing data, not genotyping array data, for returning health-related results to reduce the complexity associated with two platforms.

Although normal tissues with somatic mutations did not necessarily progress to cancer, researchers saw a jump in mutational burden in samples associated with cancer or cirrhosis.

Tumor genomes from almost 2,400 patients with metastatic cancer revealed a range of somatic alterations, providing a foundation for clinical sequencing efforts.

In Nucleic Acids Research this week: ways to find cell death or proliferation signatures, Han Chinese population genome database, and more.

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In a cartoon, Vox explores the lack of women among this year's winners of the Nobel Prize.

Nature Biotechnology discusses promising early results from two clinical trials of CRISPR-based therapy for β-thalassemia and sickle cell disease.

In Cell this week: analysis of tissue clones, metagenomic studies of ocean water samples, and more.

Forensic genetic firm Verogen has bought the genetic genealogy site GEDmatch.