With plasmid and chromosomal sequence data, European investigators identified three main routes for carbapenem antibiotic resistance spread in Klebsiella pneumoniae.
Interim results from a study in the Netherlands suggest whole-genome sequencing can be done fast enough to uncover treatment targets in metastatic cancer patients.
Researchers studied the genetic structure of Viking Age Scandinavian populations, along with migrations and the adoption of Viking culture by non-Scandinavians.
By combining genome sequence data with phylogenetics and other clues, two teams looked at the SARS-CoV-2 introductions that sparked outbreaks in North America and Europe.
A pilot study enrolling up to 15 patients will validate CapeDx's utility to match patients to approved drugs and clinical trials based on whole-genome and tumor sequencing.
Researchers from MedGenome, Genentech, and multiple international institutions found potentially actionable alterations in more than 200 gallbladder cancer samples.
Using sequence data from nearly 2,500 isolates submitted to GISAID before April, researchers tallied coding and non-coding changes in the virus across locations and conditions.
The sequence-based analysis suggests oncogene-containing circular, extrachromosomal sequences occur in most cancer types and may correspond with poorer patient outcomes.
