vaccines

Results from a recent study suggest that considering nearby variants can improve the accuracy of neoantigen selection, resulting in better personalized vaccines for patients.

The companies will use Natera's Signatera circulating tumor DNA assay to assess response to NEO-PV-01, a clinical trial-stage neoantigen cancer vaccine.

The grant will support the consortium's ongoing efforts to clinically validate data analysis software for monitoring treatment responses to cancer vaccines.

Very Own Vaccine

Researchers find that a personalized ovarian cancer vaccine appears safe, the Los Angeles Times reports.

Faster Flu Vaccines?

Synthetic Genomics is working on speeding up flu vaccine production, according to the San Diego Union-Tribune.

First Stages

Early trial of experimental gene-based Zika vaccine indicates it is tolerated and leads to an antibody response.

The Universal Influenza Vaccine Initiative, led by Vanderbilt and the Human Vaccines Project, has turned to omics and AI to create more effective flu vaccines.

This Week in PNAS

In PNAS this week: grape genomes give insight into domestication, columnar cacti classification, and more.

Not Cow, But Horse

The sequencing of a more than 100-year-old smallpox vaccine finds that it contains horsepox, researchers write in NEJM.

Neon Therapeutics is sponsoring a Phase Ib trial of neoantigen-based vaccines in combination with anti-PD-1 treatment in melanoma, lung cancer, and bladder cancer.

Pages

John Mendelsohn, a former president of the University of Texas MD Anderson Cancer Center, has died, the New York Times reports.

Chinese state news agency Xinhua reports that a preliminary investigation has found He Jiankui performed his gene-editing work illegally.

Identical twins receive different estimates of ancestry from the same direct-to-consumer genetic testing firms, CBC reports.

In PNAS this week: chromosomal features of maize, adaptations in the vinous-throated parrotbill, and more.