tumor sequencing Breast Cancer Genomics Study Reveals Recurrent Contributors to Treatment Resistance in Early Disease Researchers saw convergent subclones crop up in early-stage, estrogen receptor-positive breast cancers that dodged endocrine- and CDK4/6 inhibitor-based therapies. Uterine Leiomyosarcoma Sequences Point to Potentially Targetable Somatic Mutations Using genome, exome, or transcriptome sequences from dozens of uterine leiomyosarcoma samples, researchers found alterations that may respond to existing targetable treatments. Cancer Heritability Gene Set Expanded With Common Variant Analysis Using a gene-level heritability analysis approach, investigators came up with a collection of genes that come together to influence the risk for more than a dozen cancer types. Natera Launches Tumor Genomic Profiling Assay, Expects Reproductive Health to Break Even This Year Premium During a conference call, company executives also discussed results from the SMART NIPT trial and their outlook for Natera's three businesses. Guardant Health Turns to Tumor Tissue Sequencing to Broaden Offering Premium With its liquid biopsy test FDA approved and monitoring and screening offerings poised for launch, the firm is turning its attention to tumor tissue testing. Dec 9, 2020 Appendiceal Cancer Sequences Suggest Distinct Mutation Patterns in Early-, Late-Onset Cases Nov 18, 2020 MSK Study Suggests Germline Tests May Miss Mosaic Cancer Risk Mutations in Some Patients Premium Nov 10, 2020 BostonGene, Thomas Jefferson University Partner on Head, Neck Cancer Research Oct 8, 2020 Germline Genetic Testing After Tumor Sequencing Can Uncover Clinically Actionable Variants Sep 25, 2020 M2Gen Expands Partnership With Discovery Life Sciences Sep 1, 2020 GenomiQa, Icon Group to Validate Genomic Analysis Platform CapeDx in Australia Aug 13, 2020 Triple-Negative Breast Cancer Treatment Hints Drawn From Single-Cell Study Jul 15, 2020 Patient Education Project Identifies Need for Consistent Terms in Cancer Testing Premium Jul 13, 2020 Genuity Science, Formerly WuXi NextCode, Reinvents Itself With US, Europe Focus Premium Jun 15, 2020 Dante Labs, Cambridge Cancer Genomics, Nonacus Collaborate to Build Tumor Profiling Service Apr 13, 2020 Pediatric Low-Grade Glioma Molecular and Clinical Analysis Defines Subtypes That Predict Outcome Mar 12, 2020 Perthera's Virtual Molecular Tumor Board Can Improve Patient Outcomes, Overcome Access Barriers Premium Feb 29, 2020 NantHealth Q4 Revenues Grow 6 Percent Feb 6, 2020 Despite Barriers, Labs Starting to Report Suspected Cancer Risk Mutations Seen in Tumor Testing Feb 5, 2020 Large-Scale Pan-Cancer Analysis Expands Set of Alterations Disrupting Key Genes, Pathways Nov 19, 2019 Despite FDA Clearance for NantHealth Test, Benefits of TMB Biomarker Unclear Premium Nov 12, 2019 FDA Clears NantHealth Tumor-Normal Whole-Exome Test Nov 7, 2019 NantHealth Q3 Revenues Increase Marginally Oct 18, 2019 Cervical Cancer Exomes Point to Potentially Targetable HER, PIK3CA Pathway Changes Sep 30, 2019 Tempus Finds Tumor-Normal Sequencing, RNA Profiling Aid Patient Matching to Therapies, Trials Load More Breaking News Alzheimer's Disease Phosphoproteomics Study Uncovers Signaling Abnormalities Genetic Analysis of H. Pylori Indicates Americas Colonized in One Main Migration Event BillionToOne Raises $55M in Series B Financing GeninCode to Launch Cardiovascular Disease Risk Tests in US With Eversana Top Five Articles on GenomeWeb Last Week: Illumina, Liquid Biopsy, Thermo Fisher Scientific, and More Becton Dickinson Sues Beckman Coulter Over Cell Analysis, Sorting IP The Scan Another Resignation According to the Wall Street Journal, a third advisory panel member has resigned following the US Food and Drug Administration's approval of an Alzheimer's disease drug. Novavax Finds Its Vaccine Effective Reuters reports Novavax's SARS-CoV-2 vaccine is more than 90 percent effective in preventing COVID-19. Can't Be Used The US Food and Drug Administration says millions of vaccine doses made at an embattled manufacturing facility cannot be used, the New York Times reports. PLOS Papers on Frozen Shoulder GWAS, Epstein-Barr Effects on Immune Cell Epigenetics, More In PLOS this week: genome-wide association study of frozen shoulder, epigenetic patterns of Epstein-Barr-infected B lymphocyte cells, and more.