Thousands of parent-child exomes helped researchers identify apparently causative mobile element insertions in a handful of children with developmental disorders.
Saturation mutagenesis of the human malaria parasite Plasmodium falciparum identified almost 2,700 essential genes during the blood stage of infection.
Researchers applied an unbiased transposon mutagenesis sequencing method called SBCapSeq to assess heterogeneity and driver mutations in a mouse model for myeloid leukemia.
The UCR researchers will conduct rice genome sequencing studies to discover how transposable elements may affect gene expression and possibly be involved in adaptation changes.
Three papers in the latest issue of Cell are providing new insights into transposons and their potential influence on everything from human genetic variation to disease risk.
