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Thousands of parent-child exomes helped researchers identify apparently causative mobile element insertions in a handful of children with developmental disorders.
In Genome Research this week: sequencing method examines proteins parasite uses to evade immune system, L1 insertions in cancer, and more.
Saturation mutagenesis of the human malaria parasite Plasmodium falciparum identified almost 2,700 essential genes during the blood stage of infection.
In PNAS this week: effector proteins contributing to Legionnaires' disease virulence, proteomic analysis of transition to quiescence, and more.
Researchers applied an unbiased transposon mutagenesis sequencing method called SBCapSeq to assess heterogeneity and driver mutations in a mouse model for myeloid leukemia.
The UCR researchers will conduct rice genome sequencing studies to discover how transposable elements may affect gene expression and possibly be involved in adaptation changes.
Three papers in the latest issue of Cell are providing new insights into transposons and their potential influence on everything from human genetic variation to disease risk.
NPR reports the US Food and Drug Administration has approved a treatment for a genetic disorder that causes rapid aging.
Late-stage testing indicates the AstraZeneca and Oxford University SARS-CoV-2 vaccine can have up to 90 percent efficacy, the Associated Press reports.
ScienceInsider reports Nature Communications is reviewing a paper on mentorship following social media criticism arguing it is sexist.
In PLOS this week: method to account for sequencing errors in phylogenies, study of influenza A in Switzerland, and more.