The two new single-cell RNA-sequencing methods aim to overcome some of the limitations of single-cell transcriptomics.
Using Pacific Biosciences reads polished with short read and transcriptome sequences, researchers generated a de novo genome assembly for Castor canadensis.
In a pair of papers, the researchers reported that the sugar pine genome largely comprises transposable elements and contains conifer-specific Dicer-like proteins.
The researchers added that these expression changes could be used to predict when a bloom might occur.
The company plans to use the proceeds to support research collaborations and to expand its commercial team.
The company plans to raise $25 million in a Series B financing round. It is also working on a two-color chemistry and aims to develop an instrument for clinical applications.
When refrigerated, tomatoes' flavor metabolome and transcriptome change, a PNAS study finds.
Lexogen's QuantSeq pipeline uses a gene-counting approach to analyze transcriptome data, and does not require users to calculate FPKM values.
In Genome Research this week: Sus scrofa genetic variants, translational plasticity might minimize effects of harmful mutations, and more.
In PLOS this week: recombinant bat coronavirus, transcriptional patterns in a hermaphroditic parasitic flatworm, and more.
In PNAS this week: carbapenem resistance in Enterobacteriaceae, selection against educational attainment-linked variants, and more.
Technology Review points out that a new US presidential science advisor hasn't been selected.
Researchers find that blood tests might be able to help determine severity of a concussion, Wired reports.
President-elect Donald Trump considers other candidates for director of the National Institutes of Health, Nature News reports.