Single-cell transcriptomic profiles for more than 1,700 malaria-causing Plasmodium berghei parasites revealed gene expression patterns that differ by parasite stage.
Using single-cell sequencing and an in vitro culture system, researchers followed transcriptomic and epigenomic features over time in three main embryonic cell lineages.
The award will go to Jocelyn Silvester of Children's Hospital Boston, to fund transcriptomics research on intestinal inflammation caused by gluten.
The company hopes to convert biopharma customers to increasingly comprehensive approaches, and intends to branch out further with blood-based exome sequencing next year.
The companies will build clinical-genomic datasets to serve medical practitioners at the point of care as well as inform drug development.
Researchers generated a spatial transcriptome of mouse embryonic germ layer tissues from the pre-gastrulation stage to the late gastrulation stage.
The method allows for the annotation of cells by their genotype and capture of single-cell transcriptomes, even when the cells aren't morphologically distinct.
Through a transcriptomic analysis, the researchers developed a catalog of gene expression with the olfactory mucosa of half a dozen mammals.
Researchers characterized new and known cell populations with single-cell transcriptome profiles for nearly 10,400 liver cells, using the data to see changes associated with liver cancer.
The partnership will make public and custom transcriptomic datasets available directly through Genestack's recently introduced Omics Data Manager system.
In a point-counterpoint in the Boston Globe, researchers discuss the potential of gene editing to prevent Lyme disease, but also the pitfalls of doing so.
The Wall Street Journal looks into FamilyTreeDNA's handling of genetic genealogy searches by law enforcement.
MIT's Technology Review reports that researchers hope to develop a CRISPR-based pain therapy.
In Science this week: atlas of malaria parasites' gene expression across their life cycles, and more.