tissue-based diagnostics

The firm's CEO said he's seeing significant growth in research applications from its RNA in-situ hybridization technology, and sees potential for its use in clinical settings.

Amid concerns about buparlisib's toxicity profile, a study suggests there might be a benefit for a subpopulation of patients with a more targeted PI3K inhibitor.

Molecular Autopsy Consortium of Houston members outlined their recommendations for using molecular autopsy to investigate unexplained deaths in young people. 

While the deal has provided AstraZeneca and MedImmune access to the tissue phenomics technology, Definiens now has broader and clearer access to patients.

 

Roche Diagnostics announced today it has purchased a technology portfolio for microdissection of slide-mounted tissue sections from AvanSci Bio.

NEW YORK (GenomeWeb) – Definiens announced today that it has raised €15 million ($20.4 million) in a private round of financing that will support the firm's efforts to expand its business into digital tissue diagnostics.

NEW YORK (GenomeWeb News) – The Translational Genomics Research Institute has struck a collaborative research agreement with Ventana Medical Systems to study new biomarkers for use in treating pancreatic cancer, Ventana said today.

NEW YORK (GenomeWeb News) – Leica Biosystems and Synthon Biopharmaceuticals announced today a collaboration to develop and commercialize companion diagnostics for drugs aimed at treating solid tumors.

NEW YORK (GenomeWeb News) – The US Food and Drug Administration has cleared for marketing Applied Spectral Imaging's GenASIs Scan & Analysis automated gene scanner as an aid in ALK gene analysis for lung cancer therapy selection, ASI said this week.

NEW YORK (GenomeWeb News) – Agilent Technologies company Dako today announced a companion diagnostic agreement with Pfizer. The deal establishes a legal framework for the two firms to carry out R&D and commercialization work as well as advisory services, Dako said.

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 Senator Lamar Alexander (R-Tenn.), who chairs the Senate health committee, will be retiring at the end of his term, Stat News reports.

UCSF researchers find that having two X chromosomes may contribute to women's longer lifespans, according to Discover's D-brief blog.

The Wall Street Journal reports on the US Centers for Disease Control and Prevention's use of genetic approaches to study foodborne illnesses.

In PNAS this week: immune cell profiling of wild baboons by social status, metabolomics profiling of esophageal tumors, and more.