tissue-based diagnostics Qiagen, Mirati Therapeutics Partner to Develop KRAS Companion Test for NSCLC Drug The tissue-based test will identify cancer patients who may benefit from adagrasib, Mirati's investigational oral small molecule inhibitor of KRAS G12C. UK Startup Gabriel Precision Oncology Leans on Congenica to Broaden NGS Use in Cancer Testing Premium Spun out of the Glasgow Precision Oncology Laboratory, Gabriel wants targeted sequencing to become the norm for all somatic cancer patients. Representative Tumor Sampling Method Promises to Lessen Bias of Molecular Analyses Premium The method, called representative sequencing, homogenizes chunks of leftover tumor tissue following pathology extraction to capture an unbiased profile of the tumor's cellular heterogeneity. FDA Clears Cancer Genomic Profiling Kit From Personal Genome Diagnostics The firm said the FDA clearance was supported by data across several lab sites and all variant classes in clinical samples from 35 tumor types. Through Mayo Clinic Pact, PGDx Hopes to Show Clinical Utility for NGS Tissue, Liquid Biopsy Assays Premium The group envisions using PGDx's technology to identify effective therapy options for cancer patients and improve monitoring of patient response to therapy. Jan 15, 2020 JP Morgan Healthcare Day 2: 10x Genomics, GenapSys, Caris, Adaptive Bio, Danaher, Agilent, Luminex Jul 25, 2019 Roche Reports Flat Diagnostics Revenues in H1 Apr 17, 2019 Roche Reports Flat Q1 Diagnostics Sales Jan 19, 2018 RNA Hybridization, Multiplex Assays Central to Bio-Techne's Growth Plans Premium Dec 9, 2016 Novartis PI3K Inhibitor Effective in Breast Cancer Subset; Psych Toxicities Dampen Enthusiasm Premium Jul 15, 2016 Ethics, Guidelines for Molecular Autopsy in Youth Sudden Death Explored by Texas Team Dec 23, 2014 Now Part of AstraZeneca, Definiens Concentrating on CDx, Ramp up into Clinical Space Premium Dec 10, 2014 Roche Buys Tissue Dissection Technology from AvanSci Bio Jun 23, 2014 Definiens Raises $20.4M in Private Financing Round Jun 25, 2013 TGen, Ventana Ink Pancreatic Cancer Biomarker Pact Mar 12, 2013 Leica, Synthon Biopharmaceuticals Partner on CDx Development Feb 15, 2013 FDA Clears ASI Gene Scanner as PGx Tool for NSCLC Feb 12, 2013 Dako, Pfizer Reach Companion Dx Deal Sep 6, 2012 Agilent Discloses Dako Earnings May 17, 2012 Agilent Buying Cancer Diagnostics Company Dako for $2.2B May 1, 2012 Dako, Genentech Partner on Regulatory Submission of CDx for Second Breast Cancer Drug Apr 30, 2012 GE Grant Funds Moffitt Breast Cancer Metastasis Marker Study Apr 27, 2012 MetaStat Licenses Metastatic Cell Dx Technology Patents Apr 12, 2012 Ventana Developing CDx for Seattle Genetics, Millenium Cancer Drug Feb 21, 2012 Dako Signs Another CDx Deal with Amgen Load More Breaking News Pediatric Medulloblastoma Subgroups May Benefit from Lower-Dose Radiation Therapy Space Radiation Shows Limited Effects on Mammalian Sperm DNA, Fertility Bluestar Genomics Sues Former Consultant, Ludwig Institute for Cancer Research Over IP Ownership New Products Posted to GenomeWeb: 10x Genomics, Swift Biosciences, Agilent Technologies, More In Brief This Week: Quantum-Si, TGen, Yale, and More People in the News: New Appointments at Invitae, PGDx, Oxford Nanopore, PacBio, More The Scan Fertility Fraud Found Consumer genetic testing has uncovered cases of fertility fraud that are leading to lawsuits, according to USA Today. Ties Between Vigorous Exercise, ALS in Genetically At-Risk People Regular strenuous exercise could contribute to motor neuron disease development among those already at genetic risk, Sky News reports. Test Warning The Guardian writes that the US regulators have warned against using a rapid COVID-19 test that is a key part of mass testing in the UK. Science Papers Examine Feedback Mechanism Affecting Xist, Continuous Health Monitoring for Precision Medicine In Science this week: analysis of cis confinement of the X-inactive specific transcript, and more.