tissue-based diagnostics

The firm's CEO said he's seeing significant growth in research applications from its RNA in-situ hybridization technology, and sees potential for its use in clinical settings.

Amid concerns about buparlisib's toxicity profile, a study suggests there might be a benefit for a subpopulation of patients with a more targeted PI3K inhibitor.

Molecular Autopsy Consortium of Houston members outlined their recommendations for using molecular autopsy to investigate unexplained deaths in young people. 

While the deal has provided AstraZeneca and MedImmune access to the tissue phenomics technology, Definiens now has broader and clearer access to patients.

 

Roche Diagnostics announced today it has purchased a technology portfolio for microdissection of slide-mounted tissue sections from AvanSci Bio.

NEW YORK (GenomeWeb) – Definiens announced today that it has raised €15 million ($20.4 million) in a private round of financing that will support the firm's efforts to expand its business into digital tissue diagnostics.

NEW YORK (GenomeWeb News) – The Translational Genomics Research Institute has struck a collaborative research agreement with Ventana Medical Systems to study new biomarkers for use in treating pancreatic cancer, Ventana said today.

NEW YORK (GenomeWeb News) – Leica Biosystems and Synthon Biopharmaceuticals announced today a collaboration to develop and commercialize companion diagnostics for drugs aimed at treating solid tumors.

NEW YORK (GenomeWeb News) – The US Food and Drug Administration has cleared for marketing Applied Spectral Imaging's GenASIs Scan & Analysis automated gene scanner as an aid in ALK gene analysis for lung cancer therapy selection, ASI said this week.

NEW YORK (GenomeWeb News) – Agilent Technologies company Dako today announced a companion diagnostic agreement with Pfizer.
The deal establishes a legal framework for the two firms to carry out R&D and commercialization work as well as advisory services, Dako said.

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Senator Elizabeth Warren (D-Mass.) has released the results of a genetic ancestry analysis, the Boston Globe reports.

Retraction Watch's Ivan Oransky and Adam Marcus report that Harvard Medical School and Brigham and Women's Hospital have recommended that more than 30 papers from a former researcher be retracted.

Thomas Steitz, who won the 2009 chemistry Nobel Prize for his ribosome work, has died, the Washington Post reports.

In PLOS this week: mechanisms for genes implicated in coronary artery disease, rumen microbes and host genetics influence cow methane production, and more.