tissue-based diagnostics

Amid concerns about buparlisib's toxicity profile, a study suggests there might be a benefit for a subpopulation of patients with a more targeted PI3K inhibitor.

Molecular Autopsy Consortium of Houston members outlined their recommendations for using molecular autopsy to investigate unexplained deaths in young people. 

While the deal has provided AstraZeneca and MedImmune access to the tissue phenomics technology, Definiens now has broader and clearer access to patients.

 

Roche Diagnostics announced today it has purchased a technology portfolio for microdissection of slide-mounted tissue sections from AvanSci Bio.

NEW YORK (GenomeWeb) – Definiens announced today that it has raised €15 million ($20.4 million) in a private round of financing that will support the firm's efforts to expand its business into digital tissue diagnostics.

NEW YORK (GenomeWeb News) – The Translational Genomics Research Institute has struck a collaborative research agreement with Ventana Medical Systems to study new biomarkers for use in treating pancreatic cancer, Ventana said today.

NEW YORK (GenomeWeb News) – Leica Biosystems and Synthon Biopharmaceuticals announced today a collaboration to develop and commercialize companion diagnostics for drugs aimed at treating solid tumors.

NEW YORK (GenomeWeb News) – The US Food and Drug Administration has cleared for marketing Applied Spectral Imaging's GenASIs Scan & Analysis automated gene scanner as an aid in ALK gene analysis for lung cancer therapy selection, ASI said this week.

NEW YORK (GenomeWeb News) – Agilent Technologies company Dako today announced a companion diagnostic agreement with Pfizer.
The deal establishes a legal framework for the two firms to carry out R&D and commercialization work as well as advisory services, Dako said.

NEW YORK (GenomeWeb News) – Through eight months ending May 31, 2012, Dako posted $242 million in revenues, Agilent Technologies disclosed in a regulatory filing after the close of the market on Wednesday, which also disclosed Dako's earnings for full-year 2011 and for the six months ended March

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A fire at a Manchester hospital may have destroyed lab equipment and data, the Guardian reports.

Researchers generate a genetic database from skeletal remains from the 1845 Franklin Expedition to the Arctic, Live Science reports.

Researchers in China have begun another trial using CRISPR/Cas9 approaches in cancer patients, according to the Wall Street Journal.

In Science this week: human DNA found in sediments from archeological sites lacking bones, and more.