Technology: GWAS

Researchers uncovered nearly a hundred loci to general risk tolerance and hundreds more to particular risky behaviors.

All Very Similar

Researchers have found that most genome-wide association study participants hail from just three countries, leading them to call for increased diversity.

This Week in Nature

In Nature this week: large Alzheimer's disease GWAS uncovers novel loci, new CRISPR interference-based approach, and more.

Further analysis linked the new loci to genes implicated in immune-related tissues and cell types, as well as to lipid-related processes, suggesting their involvement in disease development

Blame the Follicles

A genome-wide association study highlights a potential role for hair follicles in acne risk, according to New Scientist.

With the recent introduction of its Reveal platform, the company behind the 1000 Genomes Project browser wants to unlock the potential of the UK Biobank dataset.

Using UK Biobank data, the researchers uncovered new variants in MC1R, as well as eight other variants, that influence whether someone has red hair.

This Week in Nature

In Nature this week: study of human-Neanderthal interbreeding, attention deficit/hyperactivity disorder risk loci reported, and more.

A Georgia Tech team found that the reliance of genome-wide association studies on European populations has skewed estimates of disease risk in other populations.

The researchers noted ties between osteoarthritis-linked variants and height, and found one risk loci that implicated the Hedgehog signaling pathway.

Pages

Researchers are refining a tool to predict a woman's risk of developing breast cancer, according to the Guardian.

According to Stat News, the partial government shutdown in the US could soon affect the ability of the Food and Drug Administration to review new drugs.

CNN reports that people's genes tend to have a greater influence on their risk of developing disease than their environment, but it varies by phenotype.

In PNAS this week: gypsy moth genome sequenced, phylogenomic analysis of Polyneopterans, and more.