targeted sequencing

Researchers looked at the prevalence and effects of whole-genome duplication events across cancers using targeted sequenced data for almost 10,000 advanced cases.

Otzi gastrointestinal tract.

An analysis of stomach and gastrointestinal samples suggests the Iceman munched on a high-fat diet of ibex, red deer, and einkorn plants before his final hike.

Researchers characterized genetic, transcriptomic, and clinical features in advanced prostate cancers that emerged from treatment.

Using bulk DNA samples produced from more than 5,000 subfossil bone fragments, researchers retraced species trajectories and extinctions over time in New Zealand.

An international team of researchers compared genetic changes that occur in the blood of people who develop acute myeloid leukemia and those who do not.

New genetic studies are providing insights into the molecular changes that occur as benign moles transition to melanoma and spread to other parts of the body by metastasis.

The researchers were able to diagnose 17 patients with short telomere syndrome based on telomere length combined with targeted sequence data.

Researchers analyzed germline mutations in 256 kidney cancer patients and found mutations that would have been missed, including therapeutically relevant ones.

This Week in PLOS

In PLOS this week: links between gut microbiome and colorectal cancer mutations, targeted sequencing uncovers genetic susceptibilities to epilepsy in Koreans, and more.

Researchers from the French Parkinson's and Movement Disorders Consortium evaluated the diagnostic yield and cost of a 127-gene panel on nearly 400 patients.

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Sometimes genetic tests give inconclusive results and provide little reassurance to patients, the Associated Press reports.

Vox wonders whether gene-editing crops will be viewed similarly as genetically modified organisms of if people will give them a try.

In Science this week: research regulation and reporting requirement reform, and more.

With H3Africa, Charles Rotimi has been working to bolster the representation of African participants and African researchers in genomics, Newsweek reports.