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targeted sequencing

With plasmid and chromosomal sequence data, European investigators identified three main routes for carbapenem antibiotic resistance spread in Klebsiella pneumoniae.

Interim results from a study in the Netherlands suggest whole-genome sequencing can be done fast enough to uncover treatment targets in metastatic cancer patients.

The company holds a leading position in reproductive testing and is expected to rapidly grow its oncology business to address a total market of $21 billion.

Researchers studied the genetic structure of Viking Age Scandinavian populations, along with migrations and the adoption of Viking culture by non-Scandinavians.

Researchers characterized more than 100 ancient equid samples stretching over some 9,000 years, spanning the early Neolithic Age to the Iron Age.

Driving the shift is a belief that standard STR testing is not always a reliable tool for determining complex family relationships.

An international team of researchers put nine immune cell sequencing methods head to head, including RNA-based and DNA-based ones, using the same T-cell sample.

With targeted sequence data on more than 500 cases of the lymphatic fluid accumulation condition, researchers found and explored lymphedema-related ANGPT2 mutations.

Thermo Fisher said the assay is the first and, so far, only FDA-approved test of its kind for a targeted treatment for RET fusion-positive NSCLC.

The trial will use Natera's Signatera test to determine patient enrollment eligibility based on the presence of ctDNA and to evaluate response based on ctDNA clearance.

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President Donald Trump might not approve the stricter standards the US Food and Drug Administration is developing for authorizing a SARS-CoV-2 vaccine, according to Politico.

Wired reports that Oxitec has now developed a genetically modified fall armyworm.

A large genetic study finds SARS-CoV-2 viruses with a certain variant are spreading more than others, according to the Washington Post.

In Nature this week: sister-chromatid-sensitive chromosome conformation capture approach, and more.