targeted sequencing Ancient Genomes from Bohemia Point to Complex Population Encounters in Central Europe With 271 new or previously sequenced genomes from Bohemia, researchers followed population dynamics in the region between some 3,600 to 6,900 years ago. Studies Show Benefits of Long-Read Sequencing in Toughest Rare Disease Cases Premium Multiple studies are showing that long reads can deliver results where short reads can't, but many barriers remain on the road to the clinic. Endometriosis Treatment Target Proposed From Genetic Analysis Researchers used linkage analyses, targeted sequencing, and genotyping to identify endometriosis-associated variants in a potentially targetable receptor coding gene. Benign Hypertension-Causing Tumors Linked to Somatic Codriver Mutations Researchers identified a double-mutant form of hypertension-causing adrenal gland tumors that appear to form in response to hormone spikes during pregnancy, puberty, or menopause. Deep-Learning Method Helps Predict Sequencing Depth From DNA Probes Premium A novel computational method from NuProbe, Rice University, and Microsoft Research relies on a recurrent neural network to predict sequencing depth with high accuracy. Jul 13, 2021 Gastric Cancer Cases Frequently Harbor Genetic Risk Variants, Suggesting Germline Testing Jul 9, 2021 Integrated Tumor, Microbiome Features Influence Immunotherapy Combo Effects in Advanced Melanoma Jul 6, 2021 Celemics, South Dakota State University Create NGS-Based Respiratory Panel for Swine Jun 29, 2021 Ancient Yersinia Pestis Shows No Link to Neolithic Population Decline Jun 29, 2021 New Single-Cell Algorithm Finds Gene Panels Used to ID Rare Cells Premium Jun 28, 2021 Obsessive Compulsive Disorder Exome Analysis Uncovers Contributions From Rare Coding Variants Jun 24, 2021 Ancient Sequencing Study Expands View of Historical Population Interactions in Southern China May 13, 2021 Genetron Health, Siemens Healthineers Partner to Promote Lung Cancer Molecular Testing in China Apr 22, 2021 Pathogenic Germline Structural Variants May Be Missed by Some Testing Approaches Apr 15, 2021 Neanderthal Population Replacement Detected Using Spanish Cave Sediments Apr 7, 2021 Ancient Sequencing Studies Provide Look at Early Modern Human Populations in Europe Mar 30, 2021 Renal Cell Carcinoma Risk Gene Representation Can Vary With Ancestry Mar 26, 2021 Ancient DNA Analysis Sheds Light on Nomadic Scythian Populations Mar 26, 2021 Genome Sequencing Identifies Myeloma Precursor Disease With High Progression Risk Mar 18, 2021 Bruker Invests in Startup Acuity Spatial Genomics Mar 16, 2021 Illumina, Geneseeq Technology to Collaborate on IVD Cancer Testing Kits in China Mar 11, 2021 Burning Rock Q4 Revenues Rise 50 Percent Mar 10, 2021 Genetic Profiling Suggests Ancient Massacre Involved Indiscriminate Killing Mar 2, 2021 Guardant360 CDx Receives CE Mark for Tumor Mutational Profiling and Tagrisso CDx Use Feb 22, 2021 Twist Bioscience, Berry Genomics Partner on Targeted NGS Assays in China Load More Breaking News Beckman Coulter, Invitae Partner to Develop NGS Library Prep Applications Sick Infants Profiled with WGS See Better Diagnosis, More Care Changes UC Santa Cruz Center for Live Cell Genomics Wins $13.5M NIH Grant Genetron Health, Impact Therapeutics Partner for Anti-Cancer Drug, CDx Development Canaccord Genuity Initiates Coverage of Pacific Biosciences With Buy Rating Alternative Genetic Counseling Approach Leads to Higher Patient Satisfaction, Study Suggests The Scan Highly Similar Researchers have uncovered bat viruses that are highly similar to SARS-CoV-2, according to Nature News. Gain of Oversight According to the Wall Street Journal, the Biden Administration is considering greater oversight of gain-of-function research. Lasker for mRNA Vaccine Work The Scientist reports that researchers whose work enabled the development of mRNA-based vaccines are among this year's Lasker Award winners PLOS Papers on Causal Variant Mapping, Ancient Salmonella, ALK Fusion Test for NSCLC In PLOS this week: MsCAVIAR approach to map causal variants, analysis of ancient Salmonella, and more.