In combination with other clinical data, the genomic subtypes were able to predict patients' outcomes and could be used to help guide treatments.
Researchers found that diagnostic autism NGS panels offered by 21 clinical labs have very little overlap and are working to create a standardized gene list.
Researchers developed a k-mer-based classification scheme to assay lncRNA function, identifying cis-repressive lncRNAs with k-mer features resembling Xist.
Researchers used fine mapping and other approaches to prioritize proposed coding and non-coding causal variants at rheumatoid arthritis- and type 1 diabetes-linked loci.
Using 16S rRNA gene sequencing, researchers detected gastric microbiome differences in people with gastric polyposis, leading to a proposed predictive model.
Individuals with higher-than-usual mutant allele frequencies after stem cell transplantation were prone to disease progression and reduced progression-free survival.
The amplicon sequencing method, called resistance mutation sequencing (RM-seq), may help in detecting resistance earlier than traditional techniques.
At a 7th century German burial site, researchers saw genetic markers from populations in northern Europe, southern Europe, and the Mediterranean.
With targeted gene sequencing data from a large set of archived tumor samples, researchers identified somatic mutations coinciding with better or worse overall survival.
Using proteomic and genetic approaches, researchers identified a histone mark called lysine benzoylation that appears to be enhanced by exposure to sodium benzoate.
Senator Elizabeth Warren (D-Mass.) has released the results of a genetic ancestry analysis, the Boston Globe reports.
Retraction Watch's Ivan Oransky and Adam Marcus report that Harvard Medical School and Brigham and Women's Hospital have recommended that more than 30 papers from a former researcher be retracted.
Thomas Steitz, who won the 2009 chemistry Nobel Prize for his ribosome work, has died, the Washington Post reports.
In PLOS this week: mechanisms for genes implicated in coronary artery disease, rumen microbes and host genetics influence cow methane production, and more.