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tandem mass tagging

Exome sequencing had lower sensitivity and specificity for finding inborn errors of metabolism than conventional screening, but appeared to refine mass spec-based results.

New instrumentation, reagents, and methods, as well as increasing interest in small and single-cell samples, could prove a boon for the technology.

Researchers brought together blood transcriptomic, metabolomic, proteomic, and immune cell profiles for dozens of West African and Australasian infants.

A preliminary analysis based on high-resolution metabolomics pointed to three blood plasma metabolites with apparent ties to active, pulmonary tuberculosis.

Scientists from Kyoto University designed reagents that labeled proteins only in the presence of zinc ions for later analysis by mass spec.

The work is part of the European Union's £6.99 million DENAMIC research project, which aims to develop tools for monitoring the neurotoxic effects of environmental pollutants on the cognitive skills and development of children.

Proteome Sciences plans to market the workflows as a discovery service performed out of its ISO-certified Frankfurt laboratory and will also use them to develop proprietary biomarker panels that it will commercialize for research and, eventually, clinical use.

Novavax has begun a phase III trial of its SARS-CoV-2 vaccine, according to the New York Times.

Vox reports that the Trump Administration may limit student visas for individuals from some countries to two years.

The governor of New York says the state will conduct its own review of any SARS-CoV-2 vaccine, NPR reports.

This week in Science: Neanderthal Y chromosomes replaced by Homo sapiens Y chromosomes, and more.