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synthetic oligonucleotides

Ohio State University researchers found that a phosphorothioate-modified DNA-crRNA duplex completely blocked the function of Cas12a.

The French startup plans to offer a precommercial version of its hardware platform to beta testers as early as the end of 2019.

By using array-synthesized guide-donor oligonucleotide pairs, the team's gene editing technique allows accurate and detectable phenotyping in yeast cells.

The deal marks the latest in a series of acquisition LGC has made in recent years to expand its presence on the nucleic acid chemistry market.

GenScript believes that CustomArray's oligonucleotide synthesis and microarray manufacturing technology will enable it to better serve its customers.

The Silicon Valley startup has launched with a proprietary automation platform, and counts CRISPR researcher Jennifer Doudna among its new investors.

The company emerged from stealth mode this month and traces roots to both rocket maker SpaceX and the shuttered sequencing company Halcyon Molecular. 

The acquisition of San Diego-based ValueGene expands IDT's presence in Southern California. 

IDT said that the acquisition is expected to expand the customer base for its custom synthetic nucleic acid business across Southeast Asia.

A paper in Nature Biotechnology showed that the guide RNAs increased genome editing efficiency in human primary T cells and hematopoietic stem cells.

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Bloomberg reports that the DNA-for-cash deal reported in Kentucky might be a more widespread scam.

St. Jude Children's Research Hospital scientists have treated infants with X-linked severe combined immunodeficiency using gene therapy in an early phase study.

St. Louis Public Radio reports that some African Americans are turning to DNA ancestry testing to help guide genealogical searches.

In Nature this week: a genomic analysis of the snailfish Pseudoliparis swirei, ancient DNA analysis gives insight into the introduction of farming to England, and more.