synthetic oligonucleotides

The French startup plans to offer a precommercial version of its hardware platform to beta testers as early as the end of 2019.

By using array-synthesized guide-donor oligonucleotide pairs, the team's gene editing technique allows accurate and detectable phenotyping in yeast cells.

The deal marks the latest in a series of acquisition LGC has made in recent years to expand its presence on the nucleic acid chemistry market.

GenScript believes that CustomArray's oligonucleotide synthesis and microarray manufacturing technology will enable it to better serve its customers.

The Silicon Valley startup has launched with a proprietary automation platform, and counts CRISPR researcher Jennifer Doudna among its new investors.

The company emerged from stealth mode this month and traces roots to both rocket maker SpaceX and the shuttered sequencing company Halcyon Molecular. 

The acquisition of San Diego-based ValueGene expands IDT's presence in Southern California. 

IDT said that the acquisition is expected to expand the customer base for its custom synthetic nucleic acid business across Southeast Asia.

A paper in Nature Biotechnology showed that the guide RNAs increased genome editing efficiency in human primary T cells and hematopoietic stem cells.

The company believes it can make oligonucleotide synthesis faster and cheaper than currently available methods, and plans to launch a platform in the next year.

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Publication of He Jiankui's work on gene-edited infants would raise ethical concerns for journals, Wired and others report.

The New York Times reports that evidence linking trauma in one generation to epigenetic effects that influence subsequent generations may be overstated.

ScienceInsider reports that US National Institutes of Health researchers were told in the fall they could not obtain new human fetal tissue.

In PNAS this week: skin pigmentation evolution among KhoeSan, biomarkers for dengue virus progression, and more.