synthetic genomics
Open-Source AI Model Aims to Analyze, Design Genomic Complex Biological Architecture
The newly released Evo 2 model can analyze complex sequence data and generatively design new functional genomic elements across all domains of life.
Church, Shendure Labs Team up to Probe Possibilities for Structural Variants in Mammalian Genomes
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The authors of two newly published papers likened their method to Perturb-seq, except that it introduces structural variants instead of gene knockouts.
UK Synthetic Genomics Firm Constructive Bio Closes $58M Series A Round
The spinout from Jason Chin's lab at the University of Cambridge offers full-genome synthesis and can expand the genetic code to include non-canonical amino acids.
In proof-of-principle experiments, the researchers replaced an entire chromosome inside of a yeast cell with one from another yeast species.
Synthetic Yeast Chromosome Progress Presented in New Publications
In multiple papers, members of the Synthetic Yeast Project consortium known as Sc2.0 described progress in producing and studying synthetic yeast chromosomes and strains.