structural variant analysis Structural Variants in Advanced Cancers Point to Effect of Treatment, Suggest Resistance Mechanisms The expressions of hundreds of genes in advanced cancers change in relation to nearby structural variant breakpoints, a new analysis has found. Variantyx Expands Into Prenatal, Cancer Testing Premium The clinical whole-genome sequencing and analysis firm is planning to add Oxford Nanopore long-read sequencing to all samples by the end of the year. Long-Read Sequencing Characterizes Structural Variants in Icelandic Population By extrapolating from long-read genome sequences from 3,622 Icelanders, researchers profiled SV alleles and associated traits or conditions in the broader population. Pathogenic Germline Structural Variants May Be Missed by Some Testing Approaches Researchers at Color Health reported that intronic data is needed to uncover pathogenic structural variants linked to hereditary cancers or cardiovascular disorders. Columbia University-led Study Highlights Bionano Optical Genome Mapping Concordance with Cytogenetics Bionano Genomics called the study, presented this week at the American College for Medical Genetics meeting, an "incredibly important milestone" for the company. Apr 8, 2021 Long-Read Genome Assemblies Have 'Blind Spots' for Structural Variant Detection Premium Mar 24, 2021 Bionano Genomics Outlines Strategy for Clinical Adoption of Optical Genome Mapping Premium Mar 23, 2021 Finnish Cardiometabolic Study Uncovers Strong Effect of Structural Variants Feb 25, 2021 Haplotype-Resolved Human Genomes Help Complete Picture of Structural Variants Feb 11, 2021 Neanderthal Gene Variant Alters Neurodevelopment in Human Brain Organoids Jan 8, 2021 Bionano Genomics Expects Up to 50 Percent Q4 Revenue Growth, Prices $88.5M Public Stock Offering Dec 23, 2020 Bionano Genomics' Stock Spikes on Study Showing Strength of Structural Variation Detection Tech Dec 8, 2020 New Methods Enable Phased Human Genome Assemblies Without Parental Data Premium Nov 13, 2020 SARS-CoV-2 Genome Study Reveals Dominant Strain Oct 1, 2020 Algorithm Uncovers New Complex Rearrangement Classes in Cancer Genomes Aug 24, 2020 Kromatid Wins NHGRI Grant to Develop Single-Cell Structural Genomics Tech for Disease Research Aug 7, 2020 Computational Tool Analyzes Noncoding Mutations to Classify Cancer Subtypes Premium Jun 19, 2020 Bionano Genomics Q1 Revenues Drop 39 Percent Jun 17, 2020 Tomato Structural Variations Linked to Gene Expression, Traits Jun 15, 2020 Genome In a Bottle Consortium Releases Structural Variant Calling Benchmark Data Premium Jun 11, 2020 Analysis of Diverse Set of Human Genomes Uncovers Novel Structural Variation May 27, 2020 GnomAD Consortium Details Range of Human Genetic Variation From Large Dataset May 27, 2020 WUSTL-led Team Compiles Human Structural Variant Resource May 15, 2020 Bionano Genomics Reports Preliminary Q1 Revenues of $1.1M May 7, 2020 Primary Immunodeficiency Study Highlights Monogenic, Common Variant Disease Contributors Load More Breaking News Epic Sciences, Biosplice Therapeutics Partner on Multiomic Profiling for Cancer Trials Hamilton, Pacific Biosciences Partner on Automating DNA Sample Prep Danaher Q4 Revenues Rise 21 Percent COVID-19 Severity Biomarker Candidates Revealed in RNA Sequencing Study Flatiron Health, Japanese Hospital Partner on Real-World GI Cancer Database Abbott Q4 Diagnostics Revenues Grow 3 Percent, Full-Year Revenues up 25 Percent The Scan Time to Act A new report urges the UK to consider regulations to protect against the misuse of genomic technologies, according to the Guardian. Fulgent Seeking Defamation Suit Fulgent Genetics says it plans to sue Los Angeles County Sheriff Alex Villanueva for defamation, the Los Angeles Times reports. Speeding Gene-Edited Crops Reuters reports that China's new trial rules will make it easier to grow gene-edited crops there. Nucleic Acids Research Papers on Viral Recombination, Pan-Cancer Mutations, SARS-CoV-2 Variability In Nucleic Acids Research this week: updated pipeline to detect viral recombination, mutational patterns in tumor samples, and more.