structural variant analysis Variantyx Expands Into Prenatal, Cancer Testing Premium The clinical whole-genome sequencing and analysis firm is planning to add Oxford Nanopore long-read sequencing to all samples by the end of the year. Long-Read Sequencing Characterizes Structural Variants in Icelandic Population By extrapolating from long-read genome sequences from 3,622 Icelanders, researchers profiled SV alleles and associated traits or conditions in the broader population. Pathogenic Germline Structural Variants May Be Missed by Some Testing Approaches Researchers at Color Health reported that intronic data is needed to uncover pathogenic structural variants linked to hereditary cancers or cardiovascular disorders. Columbia University-led Study Highlights Bionano Optical Genome Mapping Concordance with Cytogenetics Bionano Genomics called the study, presented this week at the American College for Medical Genetics meeting, an "incredibly important milestone" for the company. Long-Read Genome Assemblies Have 'Blind Spots' for Structural Variant Detection Premium Researchers comparing structural variant detection using short- and long-read technologies said assembly-based methods can provide added value, despite missing certain CNVs. Mar 24, 2021 Bionano Genomics Outlines Strategy for Clinical Adoption of Optical Genome Mapping Premium Mar 23, 2021 Finnish Cardiometabolic Study Uncovers Strong Effect of Structural Variants Feb 25, 2021 Haplotype-Resolved Human Genomes Help Complete Picture of Structural Variants Feb 11, 2021 Neanderthal Gene Variant Alters Neurodevelopment in Human Brain Organoids Jan 8, 2021 Bionano Genomics Expects Up to 50 Percent Q4 Revenue Growth, Prices $88.5M Public Stock Offering Dec 23, 2020 Bionano Genomics' Stock Spikes on Study Showing Strength of Structural Variation Detection Tech Dec 8, 2020 New Methods Enable Phased Human Genome Assemblies Without Parental Data Premium Nov 13, 2020 SARS-CoV-2 Genome Study Reveals Dominant Strain Oct 1, 2020 Algorithm Uncovers New Complex Rearrangement Classes in Cancer Genomes Aug 24, 2020 Kromatid Wins NHGRI Grant to Develop Single-Cell Structural Genomics Tech for Disease Research Aug 7, 2020 Computational Tool Analyzes Noncoding Mutations to Classify Cancer Subtypes Premium Jun 19, 2020 Bionano Genomics Q1 Revenues Drop 39 Percent Jun 17, 2020 Tomato Structural Variations Linked to Gene Expression, Traits Jun 15, 2020 Genome In a Bottle Consortium Releases Structural Variant Calling Benchmark Data Premium Jun 11, 2020 Analysis of Diverse Set of Human Genomes Uncovers Novel Structural Variation May 27, 2020 GnomAD Consortium Details Range of Human Genetic Variation From Large Dataset May 27, 2020 WUSTL-led Team Compiles Human Structural Variant Resource May 15, 2020 Bionano Genomics Reports Preliminary Q1 Revenues of $1.1M May 7, 2020 Primary Immunodeficiency Study Highlights Monogenic, Common Variant Disease Contributors Apr 2, 2020 Bionano Prices $18M Stock, Warrant Offering Load More Breaking News Alzheimer's Disease Phosphoproteomics Study Uncovers Signaling Abnormalities Genetic Analysis of H. Pylori Indicates Americas Colonized in One Main Migration Event BillionToOne Raises $55M in Series B Financing GeninCode to Launch Cardiovascular Disease Risk Tests in US With Eversana Top Five Articles on GenomeWeb Last Week: Illumina, Liquid Biopsy, Thermo Fisher Scientific, and More Becton Dickinson Sues Beckman Coulter Over Cell Analysis, Sorting IP The Scan Another Resignation According to the Wall Street Journal, a third advisory panel member has resigned following the US Food and Drug Administration's approval of an Alzheimer's disease drug. Novavax Finds Its Vaccine Effective Reuters reports Novavax's SARS-CoV-2 vaccine is more than 90 percent effective in preventing COVID-19. Can't Be Used The US Food and Drug Administration says millions of vaccine doses made at an embattled manufacturing facility cannot be used, the New York Times reports. PLOS Papers on Frozen Shoulder GWAS, Epstein-Barr Effects on Immune Cell Epigenetics, More In PLOS this week: genome-wide association study of frozen shoulder, epigenetic patterns of Epstein-Barr-infected B lymphocyte cells, and more.