structural variant analysis Nabsys to Take Another Shot at Commercializing Electronic Genome Mapping Technology Next Year Premium The Providence, Rhode Island-based firm plans to release its electronic genome mapping technology for human genome applications. Analysis of 150K UK Biobank Genomes Leads to Discovery of New Variants, Trait Associations With whole-genome sequences for 150,119 UK Biobank participants, researchers tallied variants, identified population clusters, and mapped conserved regions with reduced diversity. Nanopore Sequencing Project Aims to Augment Existing 1000 Genomes Dataset Premium Researchers at the University of Washington kicked off a consortium to reanalyze all samples in the 1000 Genomes Project with nanopore long-read sequencing. Structural Variant Study Points to Pediatric Glioma Drivers, Prognostic Features Researchers profiled structural variant patterns in 179 pediatric high-grade glioma cases, identifying SV features linked to tumor subtypes and clinical outcomes. Genomic Study Reveals Recurrent Inversion Variants, Instability Effects Genomic data for 41 individuals representing 82 haplotypes helped unearth recurrent inversion polymorphisms, including variants overlapping with disease-related sites. Mar 15, 2022 Structural Variants Influence Brain Gene Expression, Disease Risk Feb 15, 2022 Sequencing Could Replace Standard Approaches for Prenatal Diagnosis of Fetal Anomalies Premium Nov 16, 2021 Structural Variants in Advanced Cancers Point to Effect of Treatment, Suggest Resistance Mechanisms May 11, 2021 Variantyx Expands Into Prenatal, Cancer Testing Premium May 10, 2021 Long-Read Sequencing Characterizes Structural Variants in Icelandic Population Apr 22, 2021 Pathogenic Germline Structural Variants May Be Missed by Some Testing Approaches Apr 16, 2021 Columbia University-led Study Highlights Bionano Optical Genome Mapping Concordance with Cytogenetics Apr 8, 2021 Long-Read Genome Assemblies Have 'Blind Spots' for Structural Variant Detection Premium Mar 24, 2021 Bionano Genomics Outlines Strategy for Clinical Adoption of Optical Genome Mapping Premium Mar 23, 2021 Finnish Cardiometabolic Study Uncovers Strong Effect of Structural Variants Feb 25, 2021 Haplotype-Resolved Human Genomes Help Complete Picture of Structural Variants Feb 11, 2021 Neanderthal Gene Variant Alters Neurodevelopment in Human Brain Organoids Jan 8, 2021 Bionano Genomics Expects Up to 50 Percent Q4 Revenue Growth, Prices $88.5M Public Stock Offering Dec 23, 2020 Bionano Genomics' Stock Spikes on Study Showing Strength of Structural Variation Detection Tech Dec 8, 2020 New Methods Enable Phased Human Genome Assemblies Without Parental Data Premium Nov 13, 2020 SARS-CoV-2 Genome Study Reveals Dominant Strain Oct 1, 2020 Algorithm Uncovers New Complex Rearrangement Classes in Cancer Genomes Aug 24, 2020 Kromatid Wins NHGRI Grant to Develop Single-Cell Structural Genomics Tech for Disease Research Aug 7, 2020 Computational Tool Analyzes Noncoding Mutations to Classify Cancer Subtypes Premium Jun 19, 2020 Bionano Genomics Q1 Revenues Drop 39 Percent Load More Breaking News Simple HealthKit Raises $8M in Series A Round Top Five Articles on GenomeWeb Last Week: Quantum-Si Layoffs, UBS Coverage Initiations, More LumiraDx Secures FDA Emergency Use Authorization, UK Approval for COVID-19, Flu Test Rarity Bioscience Raises Additional €500,000 Cancer Prognoses Informed by Module-Based Approach, Study Finds The Scan UK Team Presents Genetic, Epigenetic Sequencing Method Using enzymatic DNA preparation steps, researchers in Nature Biotechnology develop a strategy for sequencing DNA, along with 5-methylcytosine and 5-hydroxymethylcytosine, on existing sequencers. DNA Biobank Developed for French Kidney Donors, Recipients The KiT-GENIE biobank described in the European Journal of Human Genetics contains DNA samples, genotyping profiles, immune patterns, and clinical features for thousands of kidney donors or transplant recipients in Nantes, France. Cardiometabolic Disease May Have Distinct Associations With Microbial Metabolites in Blood, Gut By analyzing gut microbes in combination with related metabolites in feces and blood, researchers in Nature Communications found distinct cardiometabolic disease relationships at each site. Study Reveals New Details About Genetics of Major Cause of Female Infertility Researchers in Nature Medicine conducted a whole-exome sequencing study of mote than a thousand patients with premature ovarian insufficiency.