structural biology
Investigators embraced recently developed computational tools, with guidance from experts, to assess whether protein structure data can help predict the effects of gene variants.
Neural Gene Ties, Psychiatric Disorder Clues Found Using Complex Structural Variant Detection Tool
With the help of a probabilistic, machine-learning approach called ARC-SV, researchers found and began characterizing the brain effects of complex structural variants.
Viral Protein Functions Teased out of Structural Comparison
Based on almost 68,000 predicted structures for viral proteins, researchers gained insights into their evolutionary relationships and function.
Synthetic Yeast Chromosome Progress Presented in New Publications
In multiple papers, members of the Synthetic Yeast Project consortium known as Sc2.0 described progress in producing and studying synthetic yeast chromosomes and strains.
Developed at the University of Cambridge, Chem-map allows in situ mapping of small molecules that bind to cellular genomic DNA or chromatin-associated proteins.