NEW YORK (GenomeWeb) – A pair of studies appearing online today in Nature are uncovering evolutionary patterns for the mammalian Y chromosome and revealing conserved Y chromosome sequences stemming from ancestral, dosage-sensitive genes that have acquired functions outside of the male re

A team from Harvard Medical School and the Allen Institute for Brain Science has developed a DNA nanoball-based scheme for sequencing RNA in situ in individual cells.

Sequencing-based strategies are at the heart of several recent studies by researchers set on surveying RNA secondary structure profiles in a given organism or cell type, adding to the structural data that can be obtained by more targeted but time-consuming methods.

NEW YORK (GenomeWeb News) – Dog domestication from a still-to-be-determined group of wild wolf ancestors likely occurred through a series of dynamic processes that began before the advent of widespread agriculture by humans, according to a new PLOS Genetics

NEW YORK (GenomeWeb News) – Mixing between two protozoan parasite subspecies is associated with differences in virulence, as well as the presentation of the sleeping sickness they cause, according to a new study in mBio this we

A newly published comparison of next-generation sequencing platforms is underscoring the notion that data from no one instrument captures all of the single nucleotide variants present in a given human genome.

A year and a half after offering its first inherited disease panel on Life Technologies' SOLiD platform, Spanish molecular diagnostics and research services company Sistemas Genómicos has increased the size of that panel and has added new panels for a number of indications.

Illumina currently holds around 66 percent of the total sequencing market, but the company's share of the desktop market is split evenly with Life Technologies' Ion Torrent PGM, according to a recent survey of 150 In Sequence readers.

This story was originally published May 14.
Beckman Coulter Genomics has received CLIA certification for its sequencing services facility as it looks to develop assays for both Sanger and next-gen sequencing platforms.


An opinion piece in the Guardian argues that President Donald Trump is uninterested in science and that might not be a bad thing for the field.

The San Francisco Chronicle reports the Veterans Affairs Health System is studying whether genetic testing can help prescribe better depression therapies.

Stat News reports that Spark Therapeutics' Luxturna is now being used to treat a wider array of patients.

In Genome Biology this week: transcription factor use among brittle stars, single-cell RNA sequencing strategy, and more.