SNP genotyping

Researchers identified truncating, psychosis-related mutations in RBM12 in a family affected by schizophrenia or other psychosis disorders.

Suspicious variants were uncovered through analyses of pediatric cancer survivors from the St. Jude Lifetime Cohort Study and Childhood Cancer Survivor Study.

The team performed a gene expression analysis to discover the new loci, bringing the total number of known risk loci associated with CAD to 73.

Researchers applied a SNP heritability model called LDAK to genetic data for a range of human traits, uncovering relatively high levels of variance explained by SNPs.

Using genome-wide gene association analyses, researchers saw intelligence-related genes and loci overlapping with those in conditions such as schizophrenia.

Researchers saw partial overlap between variants influencing age-related methylation and neuronal patterns and those implicated in other traits or diseases.

Geneticure has raised around $1.1 million to fund the study, which may very well be the largest prospective RCT for personalization of high blood pressure treatment.

This Week in PNAS

In PNAS this week: horizontal gene transfer in grasses, selection patterns in great apes, and more.

Genetic analysis indicated that he was infected with a strain now found in south-central and western Asia.

Backed by €15 million in EU funding, the Ubiquitous Pharmacogenomics Consortium seeks to implement preemptive testing at seven healthcare systems by 2020.

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Gene drives might run into biological resistance, the Economist reports.

Forensic experts exhumed painter Salvador Dalí's body to collect DNA for a paternity test, CBS News reports.

Yale Environment 360 writes that synthetic and conservation biologists aren't always on the same wavelength, but they are trying to reach an understanding.

In Science this week: full CRISPR locus integration complex structure, and more.