The signature is enriched for genes involved in immune-related processes, such as T cell co-stimulation and antigen presentation, and suggests personalized treatments.
Investigators calculated that the new assay, which includes 67 SNPs, could offer a 50 percent improvement over previous methods if used in newborn screening.
At the Precision Medicine World Conference, researchers from Sanford Health, Providence Health, and Israel's Maccabi discussed their genomics programs.
Given that genetic susceptibility to schizophrenia is highly polygenic, the researchers found that the risk scores had some utility as prognostic biomarkers.
Using SNP profiles, gut microbe metagenomics, and other data, researchers identified host and microbe factors influencing circulating levels of CVD markers.
Cytox will work with AIBL to test new algorithms for identifying individuals most at risk for developing Alzheimer's disease using its current technologies.