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The deal marks the latest move by RXi to expand its access to new delivery approaches, and may offer some clues as to the therapeutic course RXi is setting for itself, which it will disclose at an investor conference this week.

Among the findings from the ongoing study was the suggestion of an anti-VEGF effect in the majority of treated patients.

The data, Tekmira President and CEO Mark Murray said in a statement, "are the first demonstration that RNAi is efficacious in an otherwise lethal primate infectious disease setting," and support the utility of RNAi in infectious diseases.

The new data in pulmonary injury and emphysema provide "support for additional clinical applications of this drug, such as treatment of acute and chronic lung injury," according to a company official.

IP Update: May 20, 2010


USPTO Publishes Three Patents, Six Patent Applications Related to RNAi

Under the deal, Bristol-Myers Squibb will use siRNAs formulated with Tekmira's stable nucleic acid-lipid particle-based delivery technology to "validate the function of certain cellular targets."

Safety data show no dose-limiting toxicities in any cohort, Quark said, supporting the drug's continued development.

The deal, which is independent of another arrangement under which Silence is developing siRNA drugs against AstraZeneca-specified targets, has been extended for one year.

According to MDRNA, the application claims siRNAs and delivery systems with therapeutic potential.

However, the company will most likely require an additional infusion of capital before it can move any of its programs into the clinic, Traversa President and CEO Hans Petersen said.


According to CNBC, Pfizer has announced that its SARS-CoV-2 vaccine data won't be ready this week.

A number of United Nations agencies push for scientific findings to be made accessible through open science.

Paris-Saclay University garners international regard following a decade-long effort to establish the new research university, Nature News reports.

In Nucleic Acids Research this week: database to house IndiGen sequencing data, database of SARS-CoV-2 docking scores, and more.