siRNA screening

With optimization work currently being done with beta testers, the company is negotiating with companies to provide their siRNA library content on its plates.

Falcon Genomics continues to work toward its goal of seeing its research-use-only Cancer Biochip System adopted in a clinical setting.

The kinase, LMTK3, regulates estrogen receptor α, which is key to patient response to endocrine therapies like tamoxifen. A study of 613 breast cancer samples linked high LMTK3 expression levels to significantly shorter disease-free survival and overall survival.

The study identified 27 genes that might impact colon cancer patients' response to oxaliplatin, a finding that could help Genomic Health add a treatment benefit indication to its Oncotype DX test.

While gene therapies may have high price tags, they could be cheaper than the cost of managing disease, according to MIT's Technology Review.

Researchers are looking for markers that indicate which cancer patients may respond to immunotherapies, the Associated Press writes.

In Nature this week: paternal age associated with de novo mutations in children, and more.

Nature News writes that researchers are still wrangling over the role of the p-value.