single-molecule sequencing New Direct Nanopore Sequencing Method Expands Toolkit for RNA Structure Profiling Premium SMS-seq combines structural probing with direct RNA nanopore sequencing, offering researchers a new way to study RNA structure at the single-molecule level. China's GeneMind Biosciences Launches GenoCare 1600 Single-Molecule Sequencer Premium The sequencing-by-synthesis platform, using technology originally developed by Helicos, was approved by China's NMPA for noninvasive prenatal testing earlier this year. Northeastern University Researchers Develop New Type of Zero-Mode Waveguide for Sequencing Premium The technology builds on the zero-mode waveguide nanotechnology underlying Pacific Biosciences' sequencing method and could be used for RNA-seq. China NMPA Approves GeneMind GenoCare 1600 Sequencer for Noninvasive Prenatal Testing The sequencer, produced by Chinese sequencing tech company GeneMind Biosciences, is approved for noninvasive prenatal testing to detect common trisomies. Pacific Biosciences Reports 3 Percent Decrease in Q4 Revenues Q4 revenues totaled $27.1 million, down from $27.9 million in Q4 of 2019 but beating the average Wall Street estimate of $25.4 million. Feb 10, 2021 Pacific Biosciences to Obtain $900M Investment From SoftBank Subsidiary Nov 24, 2020 Startup Angstrom Bio Plans Saliva-Based COVID-19 Nucleic Acid Test on Nanopore Sequencing Platform Premium Oct 22, 2020 Invitae, Pacific Biosciences Collaborate on NGS-Based Pediatric Epilepsy Testing Oct 15, 2020 Pacific Biosciences, Children's Mercy, Microsoft Collaborate on Rare Genetic Disease Diagnostics Oct 8, 2020 Pacific Biosciences' New Sequel IIe System Puts Focus on High Read Accuracy Premium Oct 2, 2020 Pacific Biosciences Upgraded to Overweight by JP Morgan Aug 12, 2020 Pacific Biosciences Prices $86.9M Public Stock Offering Aug 3, 2020 Pacific Biosciences Q2 Revenues Drop 14 Percent Aug 3, 2020 Pacific Biosciences, Asuragen Collaborate on Clinical Assays May 19, 2020 Personal Genomics Sues Pacific Biosciences in Chinese Court for Patent Infringement May 6, 2020 Pacific Biosciences Q1 Revenues Down 5 Percent Mar 18, 2020 Jury Invalidates Pacific Biosciences Patents in Lawsuit Against Oxford Nanopore Feb 11, 2020 New Algorithms Unlock Targeted Sequencing on Nanopore Platforms Premium Feb 10, 2020 Nanopore Sequencing-Based Mapping Methods Reveal Open Chromatin, Methylation Patterns Premium Feb 7, 2020 Pacific Biosciences Targets China Clinical Market to Rebound After Illumina Deal Falls Through Premium Feb 6, 2020 Pacific Biosciences Q4 Revenues Jump 43 Percent Nov 25, 2019 Oxford Nanopore Rejects Illumina's Expanded IP Offer, Suggests NovaSeq Divestiture Nov 7, 2019 Pacific Biosciences Q3 Revenues Grow 21 Percent, Miss Expectations Sep 27, 2019 Taiwanese Firm Sues Pacific Biosciences for Patent Infringement Jul 18, 2019 European Patent Office Revokes Second Pacific Biosciences Patent Load More Breaking News Simple HealthKit Raises $8M in Series A Round Top Five Articles on GenomeWeb Last Week: Quantum-Si Layoffs, UBS Coverage Initiations, More LumiraDx Secures FDA Emergency Use Authorization, UK Approval for COVID-19, Flu Test Rarity Bioscience Raises Additional €500,000 Cancer Prognoses Informed by Module-Based Approach, Study Finds The Scan UK Team Presents Genetic, Epigenetic Sequencing Method Using enzymatic DNA preparation steps, researchers in Nature Biotechnology develop a strategy for sequencing DNA, along with 5-methylcytosine and 5-hydroxymethylcytosine, on existing sequencers. DNA Biobank Developed for French Kidney Donors, Recipients The KiT-GENIE biobank described in the European Journal of Human Genetics contains DNA samples, genotyping profiles, immune patterns, and clinical features for thousands of kidney donors or transplant recipients in Nantes, France. Cardiometabolic Disease May Have Distinct Associations With Microbial Metabolites in Blood, Gut By analyzing gut microbes in combination with related metabolites in feces and blood, researchers in Nature Communications found distinct cardiometabolic disease relationships at each site. Study Reveals New Details About Genetics of Major Cause of Female Infertility Researchers in Nature Medicine conducted a whole-exome sequencing study of mote than a thousand patients with premature ovarian insufficiency.