single-molecule barcoding
Broad Institute, MIT Researchers Probe Genome Structure With New In Situ DNA Sequencing Method
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The method, published in Science, pairs in situ sequencing with NGS using barcodes to provide spatial information on DNA sequences inside tissues.
Startup Angstrom Bio Plans Saliva-Based COVID-19 Nucleic Acid Test on Nanopore Sequencing Platform
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Angstrom Bio is developing a rapid, scalable coronavirus test that uses nanopore sequencing to detect barcoded PCR products.
Developed by researchers at Yale University, the method, called deterministic barcoding in tissue sequencing, can map thousands of genes at 10 micron resolution.
Double-Barcoded Single-Cell Library Prep Solves Index-Hopping Issues, Lowers Sequencing Costs
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Two companies offering droplet-based single-cell RNA sequencing sample prep, 10x Genomics and 1Cellbio, have launched dual-indexed library preparation products.
Omics-Driven Drug Discovery Firm Octant Raises $30M in Series A Financing Round
Silicon Valley venture capital firm Andreessen Horowitz led the round, joined by 8VC, SV Angel, Allen & Co, and several other undisclosed private investors.