single molecule barcoding

By using array-synthesized guide-donor oligonucleotide pairs, the team's gene editing technique allows accurate and detectable phenotyping in yeast cells.

The team plans to eventually implement the MSI test clinically to determine whether patients are eligible for immunotherapy.

The planned instrument will help provide spatial information on both protein and RNA in tumor samples and will be powered by nCounter technology.

The chemistry will be single-molecule, based on hybridization, and will not require amplification, enzymes, or library prep, the firm said.

The company launched the BD FACSseq flow cytometer and BD Precise Assays for high-throughput single-cell gene-expression analysis studies at the ASHG annual meeting.

The solutions will combine RainDance's digital droplet technology and single-molecule barcoding technology with PacBio's proprietary long-range DNA amplification technology.

NEW YORK (GenomeWeb News) – A federal court has ruled in Illumina's favor in a lawsuit filed by Helicos BioSciences that had alleged patent infringement.

William Young said the firm's platform — which uses digital barcoding to enable multiplexed, direct profiling of individual molecules in a single reaction without amplification — is currently deployed for research purposes, but he sees a big opportunity in diagnostics and pharmacogenomics.

The Associated Press reports that the US government wasted $341,000 on travel by former Health and Human Services Secretary Tom Price.

Women who post YouTube science videos get more critical comments and more comments about their appearance than male video hosts, the New York Times reports.

The Wall Street Journal writes that participating in genetic research brings up the specter of past research ethics lapses for some African Americans.

In PLOS this week: sequences influencing yeast prion aggregation or degradation, dengue virus genetic variants affect transmission dynamics, and more.