single molecule barcoding

The companies will work on applying barcoding technology to single-cell measurements of gene and protein expression and to immune cell profiling.

By using array-synthesized guide-donor oligonucleotide pairs, the team's gene editing technique allows accurate and detectable phenotyping in yeast cells.

The team plans to eventually implement the MSI test clinically to determine whether patients are eligible for immunotherapy.

The planned instrument will help provide spatial information on both protein and RNA in tumor samples and will be powered by nCounter technology.

The chemistry will be single-molecule, based on hybridization, and will not require amplification, enzymes, or library prep, the firm said.

The company launched the BD FACSseq flow cytometer and BD Precise Assays for high-throughput single-cell gene-expression analysis studies at the ASHG annual meeting.

The solutions will combine RainDance's digital droplet technology and single-molecule barcoding technology with PacBio's proprietary long-range DNA amplification technology.

NEW YORK (GenomeWeb News) – A federal court has ruled in Illumina's favor in a lawsuit filed by Helicos BioSciences that had alleged patent infringement.

William Young said the firm's platform — which uses digital barcoding to enable multiplexed, direct profiling of individual molecules in a single reaction without amplification — is currently deployed for research purposes, but he sees a big opportunity in diagnostics and pharmacogenomics.

The New York Times and ProPublica look into the close relationship between a startup and Memorial Sloan Kettering Cancer Center.

Yahoo News reports millions of dollars are being transferred from NIH, CDC, and other programs to pay for the housing of detained undocumented immigrant children.

In Science this week: in vitro generation of human reproductive cells, and more.

Researchers gave a handful of octopuses MDMA to find that they too act more social on the drug, Gizmodo reports.