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single molecule array

Under the terms of the deal, Quanterix's single-molecule arrays will be manufactured on optical discs by Sony DADC, creating what the firms claim will be the first diagnostic consumable available in such a format.

Sony DADC's optical disc technology will provide Quanterix "with a consumable that meets the requirements of high sensitivity diagnostic testing," said a Quanterix official.

Quanterix aims to develop and manufacture an automated instrument for its SiMoA technology, which will use the "smart consumables" to support a menu of diagnostic tests.

The figure comes from a report commissioned by proteomics firm Proteome Sciences, which, like a number of other protein biomarker firms including Quanterix, Rules-Based Medicine, and NextGen Sciences, has made AD a significant focus of its R&D and commercialization efforts.

Using the company's Single Molecule Array protein detection platform, the scientists found increased levels of Alzheimer's biomarker Abeta1-42 in the blood of heart attack patients, suggesting a relationship between AD and cardiovascular conditions that reduce oxygen levels in the brain.

The firm is currently developing a research-use-only version of the instrument that it expects to launch in 2013 with an FDA-approved version coming sometime after that. It plans to manufacture the RUO device through an outside vendor because most of its parts are off-the-shelf.

The deal focuses on an undisclosed neuron-specific protein target.

The offering, which dates its first sale to Sept. 28, is in the form of options, warrants, or rights to acquire another security and is expected to last no longer than one year. As of Oct. 11, nine investors had invested in the offering, the company said.

The results offer the prospect for improved detection and measurement of low-concentration proteins – a development that has potentially broad applications in protein biomarker research, diagnostics, and drug development, David Duffy, senior director of platform research at Quanterix, told ProteoMonitor.

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