Investigators are searching for non-invasive biomarkers of rejection and earlier stage graft injury in children and adults who have received kidney transplants.
The group has filed a patent on the method and is interested in teaming up with an industry partner to commercialize it.
The researchers plan to profile patients with both Adaptive Biotechnologies' ImmunoSeq platform and 10x Genomics' single-cell immune repertoire profiling technology.
With growing interest in single-cell sequencing, researchers are looking to increase the throughput while also reducing cost.
In Nature this week: 90 ancient Egyptian mitochondrial genomes analyzed, and more.
These cell subtypes could help researchers gain a clearer understanding of cell mechanics and find better targets for potential therapies.
The LIANTI method uses linear amplification to reduce biases and could have utility in preimplantation genetic screening to detect sub-chromosomal alterations.
The Harvard spinout is commercializing inDrop single-cell sequencing technology developed by Allon Klein.
In Science this week: sequencing study of IDH glioma origins, and more.
A method called genome architecture mapping, or GAM, brings together deep DNA sequencing and laser microdissected slices of individuals cells in a tissue sample.
A Harvard University professor has been charged with making false claims regarding funds he received from China, the New York Times reports.
Discover magazine reports that animal dissections might dissuade students from science careers, but that a firm has developed synthetic frogs for dissections.
Nature News reports that a US panel is reviewing current guidelines for federally funded gain-of-function viral research.
In PNAS this week: de novo mutation patterns among the Amish, an alternative RNA-seq method, and more.