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single-cell sequencing

In Genome Biology this week: trait-related gene expression in maize, single-cell RNA sequencing of intracellular bacteria and their hosts, and more.

Such an atlas could enable investigators to understand how genetic variants impact disease risk, define drug toxicities, improve therapies, and advance regenerative medicine.

The startup is launching an instrument that will process up to 10,000 single cells for DNA sequencing as well as a panel that will target AML genes. 

A new set of papers reveals a range of gene expression influencers, identified using thousands of samples collected for the Genotype-Tissue Expression project.

The researchers plan to evaluate cfDNA and single cells isolated from the urine of patients who have had kidney transplants to identify signs of graft failure.

In Science this week: ancient Neanderthal and human genomes, and more.

In Genome Biology this week: computational approach for analyzing noisy single-cell sequencing profiles, eQTLs of dilated cardiomyopathy, and more.

In Science this week: neutrophils rely on microRNA to protect against lung inflammation, and more.

The system uses microfluidics and real-time image analysis to isolate single cells and provide visual documentation of monoclonality.

Research groups from the Broad Institute and the University of Washington have developed protocols to sequence RNA from large numbers of single nuclei and single cells. 

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23andMe has a holiday popup shop at a mall and could open additional stores, Bloomberg reports.

By studying koalas and a retrovirus that infects them, researchers may have uncovered a new sort of 'immune response' that occurs at the genomic level, Agence France Presse reports.

NPR reports that the first person in the US given a gene editing-based therapy for a genetic disorder is heading home.

In Science this week: ancient genomes reveal social inequality within individual households, new method for quantifying genetic variation in gene dosage, and more.