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single-cell sequencing

Researchers from Peking University used their method, called scTrio-seq2, to characterize and trace genetic lineages of colorectal cancer cells.

For a study published in Molecular Cell this month, researchers at Tsinghua University tested and compared three droplet-based single-cell RNA sequencing methods.

Users expressed concern that Illumina would have an even tighter grip on the sequencing market but are optimistic that it would spur development of PacBio's technology.

The projects are organized by the Eliminate Cancer Initiative, the National Brain Tumor Society, and the Pediatric Brain Tumor Foundation.

In Science this week: series of reviews about gene modification, and more.

Axolotl

Using single-cell RNA sequencing and reporter lineage tracking, researchers delved into the cellular and molecular processes of axolotl limb regeneration.

The firm aims to launch the new assay in the first quarter of next year and plans to develop other products for single-cell sequencing library prep.

The group plans to use the method to analyze isoform differences of B cell surface receptors, common targets for immunotherapy.

The RNA-seq data, for nearly 40,000 cells from the developing mouse brain, can be explored through an interactive online interface called Cell Seek.

In Genome Research this week: queen bee chromatin profiles, quantitative trait loci and allele-specific expression in wild house mice, and more.

Pages

The Washington Post reports that the CDC's SARS-CoV-2 test issues reflect earlier ones it had with Zika virus testing.

NPR writes that even with thousands of new COVID-19 papers, each should be evaluated based on its own quality.

Researchers traced a gene cluster linked to COVID-19 severity to Neanderthals, the New York Times reports.

In PNAS this week: soil bacteria-derived small molecules affect centrosomal protein, microfluidics approach for capturing circulating tumor cells, and more.