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single-cell sequencing

Diverse strategies for sequencing single cells were front and center at this year's annual Biology of Genomes meeting at Cold Spring Harbor Laboratory in New York, with four researchers presenting information on methods to sequence individual cells as part of cancer, genetic mapp

By Monica Heger

This article was originally published April 2.

By Monica Heger

This article was originally published March 19.

By Monica Heger
Despite the technical challenges of single-cell sequencing, researchers have begun using the technique to better study single bacterial species from metagenomic samples.

The competition, part of a $7 million "Grand Challenges" program that Life Tech launched last year, will award a $1 million prize to the first SOLiD user who succeeds in sequencing the genome and transcriptome of a single cancer cell.

There are two main problems when it comes to sequencing single cells: Whole-genome amplification protocols do not amplify the genome in an unbiased manner, and PCR steps in library preparation introduce additional biases and errors.

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Retraction Watch writes that a cancer researcher has had an eighth paper retracted.

Computational biologist James Taylor has died, according to Johns Hopkins University.

The Centers for Disease Control and Prevention is starting to test people for SARS-CoV-2 antibodies, according to the New York Times.

In PLOS this week: features of tumor-infiltrating immune cells, regulatory effects of SNPs associated with prostate cancer risk, and more.