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single-cell sequencing

NEW YORK (GenomeWeb) — Cells that make up brain tumors are more heterogeneous than previously thought, according to a new single-cell transcriptomic analysis appearing in Science today.

NEW YORK (GenomeWeb) – Researchers from the US, Malawi, and the UK recently debuted a single-cell sequencing strategy aimed at characterizing the diversity across individual malaria parasites — an approach that's expected to prove particularly useful for understanding features of so-called multip

NEW YORK(GenomeWeb News) – The University of Perugia's Agostinho Carvalho and colleagues explored the influence that polymorphisms in a gene called PTX3 — known for its role in mediating immune responses to fungi — might have on an individual's risk of developing invasive aspergillosis infections

In 2013, single-cell sequencing dominated much of the research space in next-generation sequencing, driven by advances in technology and dropping costs of sequencing.

Researchers at the Karolinska Institute in Sweden have developed a single-cell transcriptome sequencing method that uses molecular tags and microfluidics to enable quantitative gene expression measurements in a single cell.

A pair of recently published studies demonstrates that a whole-genome amplification-based single-cell sequencing technique known as MALBAC —multiple annealing and looping-based amplification cycles — can be applied in the clinic for prenatal genetic diagnosis and monitoring circu

This article was originally published Nov. 11.

By modifying steps in an existing library preparation protocol, a Swedish team has found ways to sequence more of the RNA present in individual cells, while generating longer RNA transcripts.

Single-cell sequencing is quickly entering the clinic with initial applications in cancer and pre-implantation genetic diagnosis and screening, researchers reported this week at the Beyond the Genome conference in San Francisco, Calif., which was sponsored by Genome Biology

Next-generation sequencing is helping to drive the emerging market in single-cell genomics, according to a report by Culver City, Calif.-based market research firm DeciBio.


The Washington Post reports on researchers' efforts to determine the effect of an increasingly common SARS-CoV-2 mutation.

Florida Politics reports Florida's law barring life, long-term care, and disability insurers from using genetic information in coverage decisions went into effect at the beginning of July.

A new analysis finds a link between popular media coverage of a scientific study and how often that paper is cited.

In Nature this week: CRISPR approaches to editing plant genomes, way to speed up DNA-PAINT, and more.