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single-cell sequencing

By sequencing RNA transcripts in hundreds of individual cells from adult and fetal brains, researchers are defining new brain cell features and subtypes.

Single-molecule biology and single-cell genomics are poised to enable precision medicine, writes Harvard's X. Sunney Xie in JAMA.

A method called G&T-seq physically separates single-cell DNA from messenger RNA for subsequent sequencing.

New analytical approaches combine single-cell RNA-seq profiles with in situ gene expression markers to place sequenced cells in a spatial context.

JGI is interested in coupling the technique with microfluidics as an automated way of picking out metabolically active cells.

The method was developed in the laboratory of Rickard Sandberg at the Ludwig Institute for Cancer Research in Stockholm and published by his group in 2013.

A Swedish team tracked down 47 cell sub-types through single-cell RNA sequencing on two mouse brain regions.

The approach combines barcoding of individual mRNA molecules from single cells with next-generation sequencing.

NEW YORK (GenomeWeb) – Before selecting a single-cell, whole-genome amplification strategy for a given study, researchers should carefully consider the genome features most crucial to the investigation at hand, according to a

NEW YORK (GenomeWeb) – Using a newly developed single-cell sequencing approach, the University of Texas MD Anderson Cancer Center's Nicholas Navin and colleagues found that mutations crop up in different types of tumor cells at different rates.

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The Washington Post reports on researchers' efforts to determine the effect of an increasingly common SARS-CoV-2 mutation.

Florida Politics reports Florida's law barring life, long-term care, and disability insurers from using genetic information in coverage decisions went into effect at the beginning of July.

A new analysis finds a link between popular media coverage of a scientific study and how often that paper is cited.

In Nature this week: CRISPR approaches to editing plant genomes, way to speed up DNA-PAINT, and more.