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single-cell sequencing

A pair of recently published studies demonstrates that a whole-genome amplification-based single-cell sequencing technique known as MALBAC —multiple annealing and looping-based amplification cycles — can be applied in the clinic for prenatal genetic diagnosis and monitoring circu

This article was originally published Nov. 11.

By modifying steps in an existing library preparation protocol, a Swedish team has found ways to sequence more of the RNA present in individual cells, while generating longer RNA transcripts.

Single-cell sequencing is quickly entering the clinic with initial applications in cancer and pre-implantation genetic diagnosis and screening, researchers reported this week at the Beyond the Genome conference in San Francisco, Calif., which was sponsored by Genome Biology

Next-generation sequencing is helping to drive the emerging market in single-cell genomics, according to a report by Culver City, Calif.-based market research firm DeciBio.

NEW YORK (GenomeWeb News) – An international team led by investigators in the US and Australia reported online yesterday in Nature that it has sequenced draft genomes for hundreds of mi

As research tools become more refined, scientists are applying single-cell genomics approaches to fill in what is known about microbial diversity.

Fluidigm has released a system and protocols to automate the processing of cells for single-cell transcriptome sequencing.

Fluidigm has launched its mRNA sequencing application for its C1 Single-Cell Auto Prep System to enable automated preparation of 96 cells for single-cell transcriptome sequencing on Illumina systems.

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The New York City Police Department will be removing DNA profiles from a local database if they are from people who were never convicted of a crime, the New York Times reports.

Science reports that accusations of sexual assault against a microbiome researcher has also led to questions about his academic certifications.

Wired reports that researchers are analyzing the DNA fish leave behind in water to study their populations.

In Science this week: comprehensive cellular map of the human thymus, evidence of admixture between the ancestors of Neanderthals and Denisovan and a 'superarchaic' population.