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In Science this week: sequencing study of IDH glioma origins, and more.
A method called genome architecture mapping, or GAM, brings together deep DNA sequencing and laser microdissected slices of individuals cells in a tissue sample.
In an AGBT presentation, one early-access user of BD's Resolve platform described how he used it to analyze gene expression from 1,200 kidney cells.
The two teams used combinatorial indexing for Hi-C and whole-genome sequencing and said that the methods could be tailored for other sequencing applications.
The two new single-cell RNA-sequencing methods aim to overcome some of the limitations of single-cell transcriptomics.
Systems will ship in early February and include droplet-based library prep and analytics functionalities.
The method allows analysis of copy number at the individual cell level with greater coverage uniformity and more reliable detection than other approaches.
Aviv Regev and Jonathan Weissman have jumped into the single-cell RNA-sequencing, pooled CRISPR screen fray.
The partners will collaborate in developing Atreca's single-cell sequencing technology to advance new cancer immunotherapies.
An international team of researchers reported that disseminated tumor cells likely arise late in tumor development.
Public health experts call for a transparent COVID-19 vaccine approval process in a letter; the Food and Drug Administration commissioner assures science-based approval.
The Verge reports that new gene-naming guidelines aim in part to avoid Excel-related name change confusion.
According to the Guardian, UK virologists say in a letter to officials that their expertise has been pushed aside in COVID-19 response plans.
In Nature this week: tuatara genome sequence aids in understanding amniote evolution, and more.