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The method allows analysis of copy number at the individual cell level with greater coverage uniformity and more reliable detection than other approaches.
Aviv Regev and Jonathan Weissman have jumped into the single-cell RNA-sequencing, pooled CRISPR screen fray.
The partners will collaborate in developing Atreca's single-cell sequencing technology to advance new cancer immunotherapies.
An international team of researchers reported that disseminated tumor cells likely arise late in tumor development.
The single-cell approach enabled them to identify gene expression in rare cell types, highlighting a previously unrecognized role for these cells in diabetes.
The researchers reported single-cell small-RNA profiling could have applications in studying tumor heterogeneity as well as for in vitro fertilization.
PacBio released an upgrade to its Sequel system last month that improves loading efficiency, which has increased average throughput and read length.
The institute has selected the firm's RNA-seq library preparation kits for use in gene expression profiling in single-cell analysis of brain cells.
The researchers will use single-cell genomics and other approaches to generate information that could ultimately be used to diagnose, monitor, and treat disease.
The funding supports development of biochemistry and microfluidics for digital droplet multiple displacement amplification.
President Donald Trump announced the US would be leaving the World Health Organization, NBC News reports.
A study of Great Danes homes in on a genomic region linked to fearfulness.
CDC head says a new analysis indicates earlier testing wouldn't have caught viral spread, NPR reports.
In PLOS this week: gene expression and epigenetics of Indonesian populations, hookworm parasite secretome, and more.