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single-cell sequencing

The researchers plan to evaluate cfDNA and single cells isolated from the urine of patients who have had kidney transplants to identify signs of graft failure.

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The system uses microfluidics and real-time image analysis to isolate single cells and provide visual documentation of monoclonality.

Research groups from the Broad Institute and the University of Washington have developed protocols to sequence RNA from large numbers of single nuclei and single cells. 

Investigators are searching for non-invasive biomarkers of rejection and earlier stage graft injury in children and adults who have received kidney transplants.

The group has filed a patent on the method and is interested in teaming up with an industry partner to commercialize it. 

The researchers plan to profile patients with both Adaptive Biotechnologies' ImmunoSeq platform and 10x Genomics' single-cell immune repertoire profiling technology. 

With growing interest in single-cell sequencing, researchers are looking to increase the throughput while also reducing cost.

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Nature News reports that genomics is being applied to trace and try to prevent additional COVID-19 waves.

Rady's Children Hospital and San Diego County are teaming up to test pediatric patients and their families for COVID-19 to gauge the spread of the virus locally, according to the San Diego Union-Tribune.

Wildlife managers aim to boost the genetic diversity of Mexican gray wolves by placing captive-born foster pups into packs with similarly aged wild pups, the Mercury News reports.

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