single-cell sequencing

The researchers plan to profile patients with both Adaptive Biotechnologies' ImmunoSeq platform and 10x Genomics' single-cell immune repertoire profiling technology. 

With growing interest in single-cell sequencing, researchers are looking to increase the throughput while also reducing cost.

This Week in Nature

In Nature this week: 90 ancient Egyptian mitochondrial genomes analyzed, and more.

These cell subtypes could help researchers gain a clearer understanding of cell mechanics and find better targets for potential therapies.

The LIANTI method uses linear amplification to reduce biases and could have utility in preimplantation genetic screening to detect sub-chromosomal alterations.

The Harvard spinout is commercializing inDrop single-cell sequencing technology developed by Allon Klein.

This Week in Science

In Science this week: sequencing study of IDH glioma origins, and more.

A method called genome architecture mapping, or GAM, brings together deep DNA sequencing and laser microdissected slices of individuals cells in a tissue sample.

In an AGBT presentation, one early-access user of BD's Resolve platform described how he used it to analyze gene expression from 1,200 kidney cells. 

The two teams used combinatorial indexing for Hi-C and whole-genome sequencing and said that the methods could be tailored for other sequencing applications.

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CNBC reports that Amazon invested in the startup Grail as it sees an opportunity for its cloud computing company in genomics.

Lawrence Krauss writes at Slate that science is needed for good public policy and should not be ignored.

Researchers are working on re-making the yeast genome from scratch, according to the Associated Press.

In Cell this week: functional profiling of Plasmodium genome, a self-inactivating rabies virus, and more.