single-cell sequencing | GenomeWeb

single-cell sequencing

An international team of researchers reported that disseminated tumor cells likely arise late in tumor development.

The single-cell approach enabled them to identify gene expression in rare cell types, highlighting a previously unrecognized role for these cells in diabetes. 

The researchers reported single-cell small-RNA profiling could have applications in studying tumor heterogeneity as well as for in vitro fertilization.

PacBio released an upgrade to its Sequel system last month that improves loading efficiency, which has increased average throughput and read length. 

The institute has selected the firm's RNA-seq library preparation kits for use in gene expression profiling in single-cell analysis of brain cells.

The researchers will use single-cell genomics and other approaches to generate information that could ultimately be used to diagnose, monitor, and treat disease.

The funding supports development of biochemistry and microfluidics for digital droplet multiple displacement amplification.

Researchers demonstrated that Strand-seq directional single-cell sequencing can be used to assemble consensus chromosome haplotypes for an individual.

In Genome Biology this week: single-cell transcriptomic study of embryonic stem cell differentiation, epigenome-wide association study of schizophrenia, and more.

Single nucleus sequencing analysis of triple-negative breast tumors indicated that copy number changes occur in bursts early in tumor evolution.

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In Science this week: genetic analysis of pollutant-tolerant fish, and more.

Researchers have found a rare carbapenem resistance gene on a US pig farm, NBC News reports.

New York officials are considering the use of a familial DNA search to get a lead on a suspect in the strangulation death of a runner.

NIH Director Francis Collins has selected a retired Army major general and cardiologist for the CEO spot at the agency's embattled Clinical Center.