single-cell sequencing

The group will combine VIB's sequencing technology with Verge's machine learning platform to study banked tissue samples at UCSD in a drug discovery effort.

The startup plans to harness single-cell genomics and computational analysis to discover therapies for autoimmune disease and cancer.

This Week in Science

In Science this week: single-cell sequencing to study zebrafish and frog embryonic development.

Researchers at the annual Association of Biomolecular Resource Facilities meeting said they are joining single-cell sequencing to other single-cell analyses.

At the Association of Biomolecular Research Facilities annual meeting this week, the ABRF Genomics Research Group presented results from its comparison of single-cell RNA sequencing platforms.

The two studies used Drop-seq RNA profiling to discover essentially all cell types and establish cell lineages in a model organism flatworm. 

The study found that resistant clones in triple-negative breast tumors existed prior to chemo, but transcriptional changes happened in response to therapy.

The researchers said the method can help subtype and identify rare cells with clinical implications in neurodevelopment and cancer.

In Genome Biology this week: transcription factor use among brittle stars, single-cell RNA sequencing strategy, and more.

The firm plans to focus research efforts on immuno-oncology and ongoing population sequencing projects, while continuing to push into the clinical market in India.

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Gene therapies could qualify for a faster US Food and Drug Administration approval process, according to Stat News.

Science speaks with the University of Michigan's Jedidiah Carlson, who has tracked population genetic discussions at white nationalist sites.

NPR reports that the US House of Representatives has passed a bill to enable terminally ill patients access to experimental drugs.

In Genome Research this week: inversion variants mapped in human, non-human primate genomes; transcriptome profiling of maize, sorghum; and more.