single-cell sequencing

These cell subtypes could help researchers gain a clearer understanding of cell mechanics and find better targets for potential therapies.

The LIANTI method uses linear amplification to reduce biases and could have utility in preimplantation genetic screening to detect sub-chromosomal alterations.

The Harvard spinout is commercializing inDrop single-cell sequencing technology developed by Allon Klein.

This Week in Science

In Science this week: sequencing study of IDH glioma origins, and more.

A method called genome architecture mapping, or GAM, brings together deep DNA sequencing and laser microdissected slices of individuals cells in a tissue sample.

In an AGBT presentation, one early-access user of BD's Resolve platform described how he used it to analyze gene expression from 1,200 kidney cells. 

The two teams used combinatorial indexing for Hi-C and whole-genome sequencing and said that the methods could be tailored for other sequencing applications.

The two new single-cell RNA-sequencing methods aim to overcome some of the limitations of single-cell transcriptomics.

Systems will ship in early February and include droplet-based library prep and analytics functionalities.

The method allows analysis of copy number at the individual cell level with greater coverage uniformity and more reliable detection than other approaches.

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Dog DNA testing finds that some purebreds might not truly be purebreds, Inside Edition reports.

Mary Beckerle has returned as director of the Huntsman Cancer Institute, according to ScienceInsider.

Smithsonian Magazine reports that environmental DNA sampling can be used to track elusive organisms.

In Genome Research this week: repetitive satellite DNA in the fruit fly, transcriptome map assembly pipeline, and more.