single-cell genomics

This Week in PNAS

In PNAS this week: computational approach to bring together single-cell data, systems genetic analysis of Anopheles gambiae polymorphism, and more.

Multi-Omics Factor Analysis looks for underlying causes of tumor variations by parsing and weighting genomic, epigenomic, transcriptomic, proteomic, and metabolomic data.

The BigSCale tool incorporates a numerical model that integrates data processing, clustering, convoluting, and differential expression analysis.

The startup plans to harness single-cell genomics and computational analysis to discover therapies for autoimmune disease and cancer.

A 30 percent decrease in instrument revenue was tempered by a 23 percent uptick in consumables revenue.

At the Association of Biomolecular Research Facilities annual meeting this week, the ABRF Genomics Research Group presented results from its comparison of single-cell RNA sequencing platforms.

The two studies used Drop-seq RNA profiling to discover essentially all cell types and establish cell lineages in a model organism flatworm. 

The company said PerkinElmer will pay A$.28 per share for its 89.9 million outstanding shares, a 100 percent premium to RHS's Feb. 23 closing price on the ASX.

Scientists at Helmholtz Zentrum München have developed a new package called Scanpy that they hope will support major analytical efforts, such as the Human Cell Atlas.

The company plans to launch a single-cell CNV assay, a single cell ATAC-seq assay, and a single-cell feature barcoding assay later this year.

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Cancer researcher Alan Rabson has died at 92, the New York Times reports.

As the National Guideline Clearinghouse goes dark, the ECRI Institute says it will pick up the slack.

In Genome Research this week: sequencing method examines proteins parasite uses to evade immune system, L1 insertions in cancer, and more.

The Atlantic reports on private Facebook support groups for people who receive unexpected parentage results from direct-to-consumer genetic tests.