single-cell gene expression analysis

In Nucleic Acids Research this week: updated Aspergillus niger genome annotation, high-throughput sequencing strategy for profiling RNA structure, and more.

The company plans to add 150 to 200 new employees and is quadrupling its space in Pleasanton, California, including a manufacturing site for its microfluidic chips.

The lawsuit comes a few days after a jury awarded Bio-Rad Laboratories $23.9 million in damages in a patent infringement suit against 10x Genomics.

Researchers identified immune activity changes in first-trimester placenta and decidua samples profiled through single-cell RNA sequencing.

OMI researchers will apply and validate 1CellBio's inDrop system to generate predictive data for patients with undiagnosed immune dysfunction conditions. 

Using a mouse model of immunotherapy resistant disease, the researchers found that this program could be targeted by an inhibitor to improve response.

Customers can explore public data for free but will need to pay to visualize private data or to obtain additional functionality like real-time cell-type predictions.

Researchers from Belgium analyzed the transcriptomes of almost 100,000 single cells from lung cancer patients, most of them stromal cells.

Two new studies have uncovered expression-defined T cell subsets that seem to coincide with better or worse outcomes in breast cancer or non-small cell lung cancer.

The BigSCale tool incorporates a numerical model that integrates data processing, clustering, convoluting, and differential expression analysis.

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Chinese state news agency Xinhua reports that a preliminary investigation has found He Jiankui performed his gene-editing work illegally.

John Mendelsohn, a former president of the University of Texas MD Anderson Cancer Center, has died, the New York Times reports.

Identical twins receive different estimates of ancestry from the same direct-to-consumer genetic testing firms, CBC reports.

In PNAS this week: chromosomal features of maize, adaptations in the vinous-throated parrotbill, and more.